A multimodal MRI-based classification signature emerges just prior to symptom onset in frontotemporal dementia mutation carriers.

Feis, Rogier A; Bouts, Mark J R J; de Vos, Frank; Schouten, Tijn M; Panman, Jessica L; Jiskoot, Lize C; Dopper, Elise G P; van der Grond, Jeroen; van Swieten, John C; Rombouts, Serge A R B

Feis, Rogier A; Bouts, Mark J R J; de Vos, Frank; Schouten, Tijn M; Panman, Jessica L; Jiskoot, Lize C; Dopper, Elise G P; van der Grond, Jeroen; van Swieten, John C; Rombouts, Serge A R B.

Afiliação

Feis RA; Department of Radiology, Leiden University Medical Centre, Leiden, The Netherlands r.a.feis@lumc.nl.
Bouts MJRJ; Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands.
de Vos F; Institute of Psychology, Leiden University, Leiden, The Netherlands.
Schouten TM; Department of Radiology, Leiden University Medical Centre, Leiden, The Netherlands.
Panman JL; Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands.
Jiskoot LC; Institute of Psychology, Leiden University, Leiden, The Netherlands.
Dopper EGP; Department of Radiology, Leiden University Medical Centre, Leiden, The Netherlands.
van der Grond J; Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands.
van Swieten JC; Institute of Psychology, Leiden University, Leiden, The Netherlands.
Rombouts SARB; Department of Radiology, Leiden University Medical Centre, Leiden, The Netherlands.

J Neurol Neurosurg Psychiatry ; 90(11): 1207-1214, 2019 11.

Article em En | MEDLINE | ID: mdl-31203211

Assuntos

Diagnóstico Precoce; Demência Frontotemporal/diagnóstico por imagem; Demência Frontotemporal/genética; Imagem Multimodal; Mutação; Sintomas Prodrômicos; Adulto; Idoso; Proteína C9orf72/genética; Estudos de Casos e Controles; Feminino; Heterozigoto; Humanos; Estudos Longitudinais; Aprendizado de Máquina; Masculino; Pessoa de Meia-Idade; Modelos Neurológicos; Neuroimagem; Testes Neuropsicológicos; Progranulinas/genética; Fatores de Tempo; Proteínas tau/genética

Palavras-chave

c9orf72, human; classification; diffusion tensor imaging; frontotemporal dementia; grn protein, human; machine learning; mapt protein, human; multimodal mri; resting-state functional mri

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diagnóstico Precoce / Demência Frontotemporal / Imagem Multimodal / Sintomas Prodrômicos / Mutação Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Neurol Neurosurg Psychiatry Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Holanda

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google