Six2 is negatively correlated with prognosis and facilitates epithelial-mesenchymal transition via TGF-ß/Smad signal pathway in hepatocellular carcinoma.

Wan, Zheng-Hua; Ma, Yun-Han; Jiang, Tian-Yi; Lin, Yun-Kai; Shi, Yuan-Yuan; Tan, Ye-Xiong; Dong, Li-Wei; Wang, Hong-Yang

Wan, Zheng-Hua; Ma, Yun-Han; Jiang, Tian-Yi; Lin, Yun-Kai; Shi, Yuan-Yuan; Tan, Ye-Xiong; Dong, Li-Wei; Wang, Hong-Yang.

Afiliação

Wan ZH; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, The Second Military Medical University, Shanghai 200438, China; National Center for Liver Cancer, The Second Military Medical University, Shanghai 201805, China; No.971 Hospital of Peoples' Liberati
Ma YH; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, The Second Military Medical University, Shanghai 200438, China; National Center for Liver Cancer, The Second Military Medical University, Shanghai 201805, China.
Jiang TY; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, The Second Military Medical University, Shanghai 200438, China; National Center for Liver Cancer, The Second Military Medical University, Shanghai 201805, China.
Lin YK; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, The Second Military Medical University, Shanghai 200438, China; National Center for Liver Cancer, The Second Military Medical University, Shanghai 201805, China.
Shi YY; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, The Second Military Medical University, Shanghai 200438, China.
Tan YX; National Center for Liver Cancer, The Second Military Medical University, Shanghai 201805, China.
Dong LW; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, The Second Military Medical University, Shanghai 200438, China.
Wang HY; International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, The Second Military Medical University, Shanghai 200438, China; National Center for Liver Cancer, The Second Military Medical University, Shanghai 201805, China; State Key Laboratory of Oncogenes an

Hepatobiliary Pancreat Dis Int ; 18(6): 525-531, 2019 Dec.

Article em En | MEDLINE | ID: mdl-31564506

Assuntos

Carcinoma Hepatocelular/metabolismo; Transição Epitelial-Mesenquimal; Proteínas de Homeodomínio/metabolismo; Neoplasias Hepáticas/metabolismo; Proteínas do Tecido Nervoso/metabolismo; Proteína Smad4/metabolismo; Fator de Crescimento Transformador beta/metabolismo; Animais; Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/mortalidade; Carcinoma Hepatocelular/patologia; Linhagem Celular Tumoral; Movimento Celular; Proliferação de Células; Intervalo Livre de Doença; Feminino; Regulação Neoplásica da Expressão Gênica; Proteínas de Homeodomínio/genética; Humanos; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/mortalidade; Neoplasias Hepáticas/patologia; Masculino; Camundongos Nus; Pessoa de Meia-Idade; Invasividade Neoplásica; Proteínas do Tecido Nervoso/genética; Carga Tumoral; Regulação para Cima

Palavras-chave

Hepatocellular carcinoma; Metastasis; Prognosis; Six2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Transformador beta / Carcinoma Hepatocelular / Proteínas de Homeodomínio / Proteína Smad4 / Transição Epitelial-Mesenquimal / Neoplasias Hepáticas / Proteínas do Tecido Nervoso Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Hepatobiliary Pancreat Dis Int Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2019 Tipo de documento: Article

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