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Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening.
Guimaraes, Pedro P G; Zhang, Rui; Spektor, Roman; Tan, Mingchee; Chung, Amanda; Billingsley, Margaret M; El-Mayta, Rakan; Riley, Rachel S; Wang, Lili; Wilson, James M; Mitchell, Michael J.
Afiliação
  • Guimaraes PPG; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States; Department of Physiology and Biophysics, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
  • Zhang R; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States.
  • Spektor R; Graduate Field of Genetics, Genomics and Development, Cornell University, Ithaca, NY, United States.
  • Tan M; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States.
  • Chung A; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States.
  • Billingsley MM; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States.
  • El-Mayta R; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States.
  • Riley RS; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States.
  • Wang L; Gene Therapy Program, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
  • Wilson JM; Gene Therapy Program, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
  • Mitchell MJ; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia
J Control Release ; 316: 404-417, 2019 12 28.
Article em En | MEDLINE | ID: mdl-31678653
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Mensageiro / Técnicas de Transferência de Genes / Nanopartículas / Lipídeos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals Idioma: En Revista: J Control Release Assunto da revista: FARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Mensageiro / Técnicas de Transferência de Genes / Nanopartículas / Lipídeos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals Idioma: En Revista: J Control Release Assunto da revista: FARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil