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Mechanism of eravacycline resistance in Acinetobacter baumannii mediated by a deletion mutation in the sensor kinase adeS, leading to elevated expression of the efflux pump AdeABC.
Shi, Yue; Hua, Xiaoting; Xu, Qingye; Yang, Yunxing; Zhang, Linyue; He, Jintao; Mu, Xinli; Hu, Lihua; Leptihn, Sebastian; Yu, Yunsong.
Afiliação
  • Shi Y; Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou, China.
  • Hua X; Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou, China. Electronic address: xiaotinghua@zju.edu.cn.
  • Xu Q; Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou, China.
  • Yang Y; Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou, China.
  • Zhang L; Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou, China.
  • He J; Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou, China.
  • Mu X; Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou, China.
  • Hu L; Department of critical care medicine, Hangzhou General Hospital of Chinese People's Armed Police, Hangzhou, China.
  • Leptihn S; Zhejiang University-University of Edinburgh Institute, School of Medicine, Hangzhou, China.
  • Yu Y; Department of Infectious Diseases, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China; Key Laboratory of Microbial Technology and Bioinformatics of Zhejiang Province, Hangzhou, China; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborati
Infect Genet Evol ; 80: 104185, 2020 06.
Article em En | MEDLINE | ID: mdl-31923725

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Tetraciclinas / Proteínas de Bactérias / Deleção de Sequência / Farmacorresistência Bacteriana / Acinetobacter baumannii Idioma: En Revista: Infect Genet Evol Assunto da revista: BIOLOGIA / DOENCAS TRANSMISSIVEIS / GENETICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Membrana Transportadoras / Tetraciclinas / Proteínas de Bactérias / Deleção de Sequência / Farmacorresistência Bacteriana / Acinetobacter baumannii Idioma: En Revista: Infect Genet Evol Assunto da revista: BIOLOGIA / DOENCAS TRANSMISSIVEIS / GENETICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China