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ZDHXB-101 (3',5-Diallyl-2, 4'-dihydroxy-[1,1'-biphen-yl]-3,5'-dicarbaldehyde) protects against airway remodeling and hyperresponsiveness via inhibiting both the activation of the mitogen-activated protein kinase and the signal transducer and activator of transcription-3 signaling pathways.
Jiang, Jun-Xia; Shen, Hui-Juan; Guan, Yan; Jia, Yong-Liang; Shen, Jian; Liu, Qi; Xie, Qiang-Min; Yan, Xiao-Feng.
Afiliação
  • Jiang JX; The Second Affiliated Hospital, Zhejiang University School of Medicine, # 88 Jiefang Rd, Hangzhou, 310009, Zhejiang Province, China.
  • Shen HJ; Zhejiang Respiratory Drugs Research Laboratory of State Food and Drug Administration of China, Zhejiang University School of Medicine, # 866 Yuhangtang Rd, Hangzhou, 310058, Zhejiang Province, China.
  • Guan Y; The Second Affiliated Hospital, Zhejiang University School of Medicine, # 88 Jiefang Rd, Hangzhou, 310009, Zhejiang Province, China.
  • Jia YL; Zhejiang Respiratory Drugs Research Laboratory of State Food and Drug Administration of China, Zhejiang University School of Medicine, # 866 Yuhangtang Rd, Hangzhou, 310058, Zhejiang Province, China.
  • Shen J; Zhejiang Respiratory Drugs Research Laboratory of State Food and Drug Administration of China, Zhejiang University School of Medicine, # 866 Yuhangtang Rd, Hangzhou, 310058, Zhejiang Province, China.
  • Liu Q; Affiliated Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Xie QM; Zhejiang Respiratory Drugs Research Laboratory of State Food and Drug Administration of China, Zhejiang University School of Medicine, # 866 Yuhangtang Rd, Hangzhou, 310058, Zhejiang Province, China.
  • Yan XF; Zhejiang Respiratory Drugs Research Laboratory of State Food and Drug Administration of China, Zhejiang University School of Medicine, # 866 Yuhangtang Rd, Hangzhou, 310058, Zhejiang Province, China.
Respir Res ; 21(1): 22, 2020 Jan 13.
Article em En | MEDLINE | ID: mdl-31931796
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Antiasmáticos / Sistema de Sinalização das MAP Quinases / Fator de Transcrição STAT3 / Remodelação das Vias Aéreas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Respir Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Asma / Antiasmáticos / Sistema de Sinalização das MAP Quinases / Fator de Transcrição STAT3 / Remodelação das Vias Aéreas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Respir Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China