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Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics.
Cho, Jae; Lee, Minhee; Cochrane, C Skyler; Webster, Caroline G; Fenton, Benjamin A; Zhao, Jinshi; Hong, Jiyong; Zhou, Pei.
Afiliação
  • Cho J; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710.
  • Lee M; Department of Chemistry, Duke University, Durham, NC 27708.
  • Cochrane CS; Department of Chemistry, Duke University, Durham, NC 27708.
  • Webster CG; Department of Chemistry, Duke University, Durham, NC 27708.
  • Fenton BA; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710.
  • Zhao J; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710.
  • Hong J; Department of Chemistry, Duke University, Durham, NC 27708 jiyong.hong@duke.edu peizhou@biochem.duke.edu.
  • Zhou P; Department of Biochemistry, Duke University Medical Center, Durham, NC 27710; jiyong.hong@duke.edu peizhou@biochem.duke.edu.
Proc Natl Acad Sci U S A ; 117(8): 4109-4116, 2020 02 25.
Article em En | MEDLINE | ID: mdl-32041866
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirofosfatases / Proteínas de Bactérias / Aciltransferases / Antibacterianos Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirofosfatases / Proteínas de Bactérias / Aciltransferases / Antibacterianos Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article