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Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non-randomised, uncontrolled, phase 1 trial.
Folegatti, Pedro M; Bittaye, Mustapha; Flaxman, Amy; Lopez, Fernando Ramos; Bellamy, Duncan; Kupke, Alexandra; Mair, Catherine; Makinson, Rebecca; Sheridan, Jonathan; Rohde, Cornelius; Halwe, Sandro; Jeong, Yuji; Park, Young-Shin; Kim, Jae-Ouk; Song, Manki; Boyd, Amy; Tran, Nguyen; Silman, Daniel; Poulton, Ian; Datoo, Mehreen; Marshall, Julia; Themistocleous, Yrene; Lawrie, Alison; Roberts, Rachel; Berrie, Eleanor; Becker, Stephan; Lambe, Teresa; Hill, Adrian; Ewer, Katie; Gilbert, Sarah.
Afiliação
  • Folegatti PM; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Bittaye M; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Flaxman A; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Lopez FR; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Bellamy D; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Kupke A; Institute of Virology, Philipps University of Marburg, Marburg, Germany; German Center for Infection Research, Thematic Translational Unit Emerging Infections, Marburg, Germany.
  • Mair C; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Makinson R; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Sheridan J; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Rohde C; Institute of Virology, Philipps University of Marburg, Marburg, Germany; German Center for Infection Research, Thematic Translational Unit Emerging Infections, Marburg, Germany.
  • Halwe S; Institute of Virology, Philipps University of Marburg, Marburg, Germany; German Center for Infection Research, Thematic Translational Unit Emerging Infections, Marburg, Germany.
  • Jeong Y; International Vaccine Institute, Science Unit, Seoul, South Korea.
  • Park YS; International Vaccine Institute, Science Unit, Seoul, South Korea.
  • Kim JO; International Vaccine Institute, Science Unit, Seoul, South Korea.
  • Song M; International Vaccine Institute, Science Unit, Seoul, South Korea.
  • Boyd A; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Tran N; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Silman D; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Poulton I; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Datoo M; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Marshall J; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Themistocleous Y; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Lawrie A; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Roberts R; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Berrie E; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Becker S; Institute of Virology, Philipps University of Marburg, Marburg, Germany; German Center for Infection Research, Thematic Translational Unit Emerging Infections, Marburg, Germany.
  • Lambe T; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Hill A; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Ewer K; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Gilbert S; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address: sarah.gilbert@ndm.ox.ac.uk.
Lancet Infect Dis ; 20(7): 816-826, 2020 07.
Article em En | MEDLINE | ID: mdl-32325038

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas Virais / Relação Dose-Resposta Imunológica / Coronavírus da Síndrome Respiratória do Oriente Médio / Imunogenicidade da Vacina Tipo de estudo: Clinical_trials / Etiology_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: Lancet Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas Virais / Relação Dose-Resposta Imunológica / Coronavírus da Síndrome Respiratória do Oriente Médio / Imunogenicidade da Vacina Tipo de estudo: Clinical_trials / Etiology_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: Lancet Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido