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COVID-19 in people living with human immunodeficiency virus: a case series of 33 patients.
Härter, Georg; Spinner, Christoph D; Roider, Julia; Bickel, Markus; Krznaric, Ivanka; Grunwald, Stephan; Schabaz, Farhad; Gillor, Daniel; Postel, Nils; Mueller, Matthias C; Müller, Markus; Römer, Katja; Schewe, Knud; Hoffmann, Christian.
Afiliação
  • Härter G; Medicover Ulm MVZ, Münsterplatz 6, 89073, Ulm, Germany. ghaerter@gmx.de.
  • Spinner CD; School of Medicine, Department of Medicine II, Technical University of Munich, University Hospital Klinikum rechts der Isar, Ismaninger Str. 22, 81675, München, Germany.
  • Roider J; Sektion Klinische Infektiologie, Medizinische Klinik und Poliklinik IV, Klinikum der Universität, Ludwig-Maximilians-Universität München, Pettenkoferstrasse 8a, 80336, München, Germany.
  • Bickel M; German Center for Infection Research (DZIF), Partner site Munich, München, Germany.
  • Krznaric I; Infektiologikum Frankfurt, Stresemannallee 3, D-60596, Frankfurt am Main, Germany.
  • Grunwald S; Zentrum für Infektiologie Berlin/Prenzelberg, Driesener Str. 11, 10439, Berlin, Germany.
  • Schabaz F; Zentrum für Infektiologie Berlin/Prenzelberg, Driesener Str. 11, 10439, Berlin, Germany.
  • Gillor D; MVZ Karlsplatz München, Karlsplatz 8, 80335, München, Germany.
  • Postel N; MVZ Innere Medizin Köln, Hohenstaufenring 59, 50674, Köln, Germany.
  • Mueller MC; Prinzmed, Sendlinger-Tor-Platz 8, 80336, München, Germany.
  • Müller M; Department of Infection Medicine, Medical Care Center, MVZ Clotten, Berliner Allee 29, 79110, Freiburg, Germany.
  • Römer K; Division of Infectious Diseases, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Hugstetter Straße 55, 79106, Freiburg, Germany.
  • Schewe K; , Stuttgart, Germany.
  • Hoffmann C; , Köln, Germany.
Infection ; 48(5): 681-686, 2020 Oct.
Article em En | MEDLINE | ID: mdl-32394344
ABSTRACT

INTRODUCTION:

Data on people living with human immunodeficiency virus (PLWH) in the current SARS-CoV-2 pandemic are still scarce. This case series of 33 PLWH patients with COVID-19 reveals symptoms and outcome in this special population.

METHODS:

Retrospective analysis of anonymized data including age, gender, HIV-associated parameters, symptoms, and outcome.

RESULTS:

Three out of 32 patients with documented outcomes died (9%). 91% of the patients recovered and 76% have been classified as mild cases. All patients were on antiretroviral treatment, of them 22 on tenofovir-containing regimen and 4 on the protease inhibitor darunavir.

CONCLUSIONS:

This preliminary case series does not support excess morbidity and mortality among symptomatic COVID-19 PLWH and with viral suppression on ART. SARS-CoV-2 infections may occur during boosted darunavir-based and/or on tenofovir-containing ART.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por HIV / HIV / Infecções por Coronavirus / Darunavir / Tenofovir / Betacoronavirus Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Infection Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Viral / Infecções por HIV / HIV / Infecções por Coronavirus / Darunavir / Tenofovir / Betacoronavirus Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Infection Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha