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A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL.
Tong, Bingqi; Spradlin, Jessica N; Novaes, Luiz F T; Zhang, Erika; Hu, Xirui; Moeller, Malte; Brittain, Scott M; McGregor, Lynn M; McKenna, Jeffrey M; Tallarico, John A; Schirle, Markus; Maimone, Thomas J; Nomura, Daniel K.
Afiliação
  • Tong B; Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, United States.
  • Spradlin JN; Novartis-Berkeley Center for Proteomics and Chemistry Technologies, University of California, Berkeley, Berkeley, California 94720, United States.
  • Novaes LFT; Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, United States.
  • Zhang E; Novartis-Berkeley Center for Proteomics and Chemistry Technologies, University of California, Berkeley, Berkeley, California 94720, United States.
  • Hu X; Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, United States.
  • Moeller M; Novartis-Berkeley Center for Proteomics and Chemistry Technologies, University of California, Berkeley, Berkeley, California 94720, United States.
  • Brittain SM; Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, United States.
  • McGregor LM; Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, United States.
  • McKenna JM; Novartis-Berkeley Center for Proteomics and Chemistry Technologies, University of California, Berkeley, Berkeley, California 94720, United States.
  • Tallarico JA; Department of Chemistry, University of California, Berkeley, Berkeley, California 94720, United States.
  • Schirle M; Novartis-Berkeley Center for Proteomics and Chemistry Technologies, University of California, Berkeley, Berkeley, California 94720, United States.
  • Maimone TJ; Novartis-Berkeley Center for Proteomics and Chemistry Technologies, University of California, Berkeley, Berkeley, California 94720, United States.
  • Nomura DK; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts 02139, United States.
ACS Chem Biol ; 15(7): 1788-1794, 2020 07 17.
Article em En | MEDLINE | ID: mdl-32568522
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiazóis / Proteínas de Fusão bcr-abl / Limoninas / Inibidores de Proteínas Quinases / Proteólise Limite: Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiazóis / Proteínas de Fusão bcr-abl / Limoninas / Inibidores de Proteínas Quinases / Proteólise Limite: Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos