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Considerations for the treatment of pancreatic cancer during the COVID-19 pandemic: the UK consensus position.
Jones, Christopher M; Radhakrishna, Ganesh; Aitken, Katharine; Bridgewater, John; Corrie, Pippa; Eatock, Martin; Goody, Rebecca; Ghaneh, Paula; Good, James; Grose, Derek; Holyoake, Daniel; Hunt, Arabella; Jamieson, Nigel B; Palmer, Daniel H; Soonawalla, Zahir; Valle, Juan W; Hawkins, Maria A; Mukherjee, Somnath.
Afiliação
  • Jones CM; Faculty of Biological Sciences, University of Leeds, Leeds, UK.
  • Radhakrishna G; Radiotherapy Research Group, Faculty of Medicine and Health, University of Leeds, Leeds, UK.
  • Aitken K; Leeds Cancer Centre, The Leeds Teaching Hospitals NHS Trust, Leeds, UK.
  • Bridgewater J; The Christie NHS Foundation Trust, Manchester, UK.
  • Corrie P; The Royal Marsden Hospital, The Royal Marsden NHS Foundation Trust, London, UK.
  • Eatock M; The Institute of Cancer Research, London, UK.
  • Goody R; University College London Cancer Institute, London, UK.
  • Ghaneh P; Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Good J; The Northern Ireland Cancer Centre, Belfast, UK.
  • Grose D; Radiotherapy Research Group, Faculty of Medicine and Health, University of Leeds, Leeds, UK.
  • Holyoake D; Leeds Cancer Centre, The Leeds Teaching Hospitals NHS Trust, Leeds, UK.
  • Hunt A; The Royal Liverpool University Hospital, Liverpool, UK.
  • Jamieson NB; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
  • Palmer DH; Beatson West of Scotland Cancer Centre, Glasgow, UK.
  • Soonawalla Z; Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK.
  • Valle JW; The Royal Marsden Hospital, The Royal Marsden NHS Foundation Trust, London, UK.
  • Hawkins MA; The Institute of Cancer Research, London, UK.
  • Mukherjee S; Wolfson Wohl Cancer Research Centre, University of Glasgow, Glasgow, UK.
Br J Cancer ; 123(5): 709-713, 2020 09.
Article em En | MEDLINE | ID: mdl-32641867
The coronavirus disease 2019 (COVID-19) pandemic epicentre has moved to the USA and Europe, where it is placing unprecedented demands on healthcare resources and staff availability. These service constraints, coupled with concerns relating to an increased incidence and severity of COVID-19 among patients with cancer, should lead to re-consideration of the risk-benefit balance for standard treatment pathways. This is of particular importance to pancreatic cancer, given that standard diagnostic modalities such as endoscopy may be restricted, and that disease biology precludes significant delays in treatment. In light of this, we sought consensus from UK clinicians with an interest in pancreatic cancer for management approaches that would minimise patient risk and accommodate for healthcare service restrictions. The outcomes are described here and include recommendations for treatment prioritisation, strategies to bridge to later surgical resection in resectable disease and factors that modify the risk-benefit balance for treatment in the resectable through to the metastatic settings. Priority is given to strategies that limit hospital visits, including through the use of hypofractionated precision radiotherapy and chemoradiotherapy treatment approaches.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Pneumonia Viral / Guias de Prática Clínica como Assunto / Infecções por Coronavirus / Consenso / Betacoronavirus Tipo de estudo: Etiology_studies / Guideline / Incidence_studies / Prognostic_studies / Risk_factors_studies Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Br J Cancer Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Pneumonia Viral / Guias de Prática Clínica como Assunto / Infecções por Coronavirus / Consenso / Betacoronavirus Tipo de estudo: Etiology_studies / Guideline / Incidence_studies / Prognostic_studies / Risk_factors_studies Limite: Humans País/Região como assunto: Europa Idioma: En Revista: Br J Cancer Ano de publicação: 2020 Tipo de documento: Article