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Attenuation of Oxidative Injury With Targeted Expression of NADPH Oxidase 2 Short Hairpin RNA Prevents Onset and Maintenance of Electrical Remodeling in the Canine Atrium: A Novel Gene Therapy Approach to Atrial Fibrillation.
Yoo, Shin; Pfenniger, Anna; Hoffman, Jacob; Zhang, Wenwei; Ng, Jason; Burrell, Amy; Johnson, David A; Gussak, Georg; Waugh, Trent; Bull, Suzanne; Benefield, Brandon; Knight, Bradley P; Passman, Rod; Wasserstrom, J Andrew; Aistrup, Gary L; Arora, Rishi.
Afiliação
  • Yoo S; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Pfenniger A; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Hoffman J; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Zhang W; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Ng J; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Burrell A; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Johnson DA; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Gussak G; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Waugh T; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Bull S; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Benefield B; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Knight BP; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Passman R; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Wasserstrom JA; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
  • Aistrup GL; Masonic Medical Research Institute, Utica, NY (G.L.A.).
  • Arora R; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL (S.Y., A.P., J.H., W.Z., J.N., A.B., D.A.J., G.G., T.W., S.B., B.B., B.P.K., R.P., J.A.W., R.A.).
Circulation ; 142(13): 1261-1278, 2020 09 29.
Article em En | MEDLINE | ID: mdl-32686471

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrilação Atrial / Terapia Genética / Regulação Enzimológica da Expressão Gênica / RNA Interferente Pequeno / Remodelamento Atrial / NADPH Oxidase 2 Limite: Animals Idioma: En Revista: Circulation Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fibrilação Atrial / Terapia Genética / Regulação Enzimológica da Expressão Gênica / RNA Interferente Pequeno / Remodelamento Atrial / NADPH Oxidase 2 Limite: Animals Idioma: En Revista: Circulation Ano de publicação: 2020 Tipo de documento: Article