CARD19, the protein formerly known as BinCARD, is a mitochondrial protein that does not regulate Bcl10-dependent NF-&#954;B activation after TCR engagement.

Rios, Kariana E; Kashyap, Anuj K; Maynard, Sean K; Washington, Michael; Paul, Suman; Schaefer, Brian C

CARD19, the protein formerly known as BinCARD, is a mitochondrial protein that does not regulate Bcl10-dependent NF-κB activation after TCR engagement.

Rios, Kariana E; Kashyap, Anuj K; Maynard, Sean K; Washington, Michael; Paul, Suman; Schaefer, Brian C.

Afiliação

Rios KE; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States.
Kashyap AK; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States; Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States.
Maynard SK; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States.
Washington M; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States.
Paul S; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States; Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States.
Schaefer BC; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States; Center for Neuroscience and Regenerative Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, United States. Electronic address: brian.sc

Cell Immunol ; 356: 104179, 2020 10.

Article em En | MEDLINE | ID: mdl-32763502

Assuntos

Proteínas Adaptadoras de Sinalização CARD/metabolismo; Proteínas Adaptadoras de Sinalização CARD/fisiologia; Receptores de Antígenos de Linfócitos T/fisiologia; Proteínas Adaptadoras de Transdução de Sinal/genética; Animais; Proteínas Reguladoras de Apoptose/metabolismo; Linfócitos T CD8-Positivos/metabolismo; Bases de Dados Genéticas; Regulação da Expressão Gênica/genética; Células HEK293; Humanos; Células Jurkat; Camundongos; Mitocôndrias/metabolismo; Mitocôndrias/fisiologia; Proteínas Mitocondriais/genética; Proteínas Mitocondriais/metabolismo; Receptores de Antígenos de Linfócitos T/metabolismo; Transdução de Sinais/genética

Palavras-chave

Bcl10; BinCARD; CARD proteins; CARD19; CBM complex; NF-κB; T cell receptor; T cell signaling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T / Proteínas Adaptadoras de Sinalização CARD Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cell Immunol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos

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