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Spliceosome mutations are common in persons with myeloproliferative neoplasm-associated myelofibrosis with RBC-transfusion-dependence and correlate with response to pomalidomide.
Chowdhury, Onima; O'Sullivan, Jennifer; Barkas, Nikolaos; Wang, Guanlin; Buck, Gemma; Hamblin, Angela; Tefferi, Ayalew; Al-Ali, Haifa K; Barosi, Giovanni; Devos, Timothy; Gisslinger, Heinz; Jiang, Qian; Kiladjian, Jean-Jacques; Mesa, Ruben; Passamonti, Francesco; Ribrag, Vincent; Schiller, Gary; Vannucchi, Alessandro M; Zhou, Daobin; McMullin, Mary Frances; Zhong, Jianhua; Gale, Robert Peter; Mead, Adam J.
Afiliação
  • Chowdhury O; NIHR Biomedical Research Centre and MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • O'Sullivan J; NIHR Biomedical Research Centre and MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Barkas N; NIHR Biomedical Research Centre and MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Wang G; NIHR Biomedical Research Centre and MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Buck G; NIHR Biomedical Research Centre and MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Hamblin A; NIHR Biomedical Research Centre and MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
  • Tefferi A; Mayo Clinic, Rochester, MN, USA.
  • Al-Ali HK; University Hospital Halle, Halle, Germany.
  • Barosi G; Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy.
  • Devos T; Department of Hematology, University Hospitals Leuven and Department of Microbiology and Immunology, Laboratory of Molecular Immunology (Rega Institute), Leuven, Belgium.
  • Gisslinger H; Medizinische Universität Wien, Vienna, Austria.
  • Jiang Q; Peking University, People's Hospital, Beijing, China.
  • Kiladjian JJ; Hôpital Saint-Louis, Paris, France.
  • Mesa R; Mays Cancer Center at UT Health San Antonio MD Anderson, San Antonio, TX, USA.
  • Passamonti F; University of Insubria, Varese, Italy.
  • Ribrag V; Cancer Campus, 11 Gustave Roussy, Villejuif, France.
  • Schiller G; Division of Hematology and Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
  • Vannucchi AM; Center for Research and Innovation of Myeloproliferative Neoplasms, AOU Careggi, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
  • Zhou D; Peking Union Medical College Hospital, Beijing, China.
  • McMullin MF; Queens University Belfast, Belfast, UK.
  • Zhong J; Bristol-Myers Squibb, New Brunswick, NJ, USA.
  • Gale RP; Haematology Research Centre, Imperial College London, London, UK.
  • Mead AJ; NIHR Biomedical Research Centre and MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK. Adam.mead@imm.ox.ac.uk.
Leukemia ; 35(4): 1197-1202, 2021 04.
Article em En | MEDLINE | ID: mdl-32770086

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Talidomida / Spliceossomos / Transfusão de Eritrócitos / Mielofibrose Primária / Mutação / Transtornos Mieloproliferativos Tipo de estudo: Diagnostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Talidomida / Spliceossomos / Transfusão de Eritrócitos / Mielofibrose Primária / Mutação / Transtornos Mieloproliferativos Tipo de estudo: Diagnostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Leukemia Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido