RNA-mediated toxicity in C9orf72 ALS and FTD.

McEachin, Zachary T; Parameswaran, Janani; Raj, Nisha; Bassell, Gary J; Jiang, Jie

McEachin, Zachary T; Parameswaran, Janani; Raj, Nisha; Bassell, Gary J; Jiang, Jie.

Afiliação

McEachin ZT; Department of Cell Biology, Emory University, Atlanta, GA 30322, USA; Laboratory for Translational Cell Biology, Emory University, Atlanta, GA 30322, USA. Electronic address: zmceach@emory.edu.
Parameswaran J; Department of Cell Biology, Emory University, Atlanta, GA 30322, USA.
Raj N; Department of Cell Biology, Emory University, Atlanta, GA 30322, USA; Laboratory for Translational Cell Biology, Emory University, Atlanta, GA 30322, USA.
Bassell GJ; Department of Cell Biology, Emory University, Atlanta, GA 30322, USA; Laboratory for Translational Cell Biology, Emory University, Atlanta, GA 30322, USA; Department of Neurology, Emory University, Atlanta, GA 30322, USA.
Jiang J; Department of Cell Biology, Emory University, Atlanta, GA 30322, USA. Electronic address: jie.jiang@emory.edu.

Neurobiol Dis ; 145: 105055, 2020 11.

Article em En | MEDLINE | ID: mdl-32829028

Assuntos

Esclerose Lateral Amiotrófica/patologia; Proteína C9orf72/genética; Demência Frontotemporal/patologia; RNA/toxicidade; Esclerose Lateral Amiotrófica/genética; Animais; Expansão das Repetições de DNA; Humanos

Palavras-chave

Amyotrophic lateral sclerosis; Antisense oligonucleotide; C9orf72; Dipeptide repeat proteins; Frontotemporal dementia; RNA foci; RNA-mediated toxicity

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Demência Frontotemporal / Proteína C9orf72 / Esclerose Lateral Amiotrófica Limite: Animals / Humans Idioma: En Revista: Neurobiol Dis Assunto da revista: NEUROLOGIA Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google