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Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency.
Zhang, Jiasheng; Velmeshev, Dmitry; Hashimoto, Kei; Huang, Yu-Hsin; Hofmann, Jeffrey W; Shi, Xiaoyu; Chen, Jiapei; Leidal, Andrew M; Dishart, Julian G; Cahill, Michelle K; Kelley, Kevin W; Liddelow, Shane A; Seeley, William W; Miller, Bruce L; Walther, Tobias C; Farese, Robert V; Taylor, J Paul; Ullian, Erik M; Huang, Bo; Debnath, Jayanta; Wittmann, Torsten; Kriegstein, Arnold R; Huang, Eric J.
Afiliação
  • Zhang J; Department of Pathology, University of California San Francisco, San Francisco, CA, USA.
  • Velmeshev D; Pathology Service 113B, San Francisco VA Health Care System, San Francisco, CA, USA.
  • Hashimoto K; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA, USA.
  • Huang YH; Department of Pathology, University of California San Francisco, San Francisco, CA, USA.
  • Hofmann JW; Department of Pathology, University of California San Francisco, San Francisco, CA, USA.
  • Shi X; Department of Pathology, University of California San Francisco, San Francisco, CA, USA.
  • Chen J; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.
  • Leidal AM; Department of Developmental and Cell Biology, University of California Irvine, Irvine, CA, USA.
  • Dishart JG; Department of Pathology, University of California San Francisco, San Francisco, CA, USA.
  • Cahill MK; Biomedical Sciences Graduate Program, University of California San Francisco, San Francisco, CA, USA.
  • Kelley KW; Department of Pathology, University of California San Francisco, San Francisco, CA, USA.
  • Liddelow SA; Department of Pathology, University of California San Francisco, San Francisco, CA, USA.
  • Seeley WW; Neuroscience Graduate Program, University of California San Francisco, San Francisco, CA, USA.
  • Miller BL; Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.
  • Walther TC; Neuroscience Graduate Program, University of California San Francisco, San Francisco, CA, USA.
  • Farese RV; Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.
  • Taylor JP; Neuroscience Institute, Department of Neuroscience & Physiology, NYU Langone Medical Center, New York, NY, USA.
  • Ullian EM; Neuroscience Graduate Program, University of California San Francisco, San Francisco, CA, USA.
  • Huang B; Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA.
  • Debnath J; Department of Neurology, Memory and Aging Center, University of California San Francisco, San Francisco, CA, USA.
  • Wittmann T; Department of Neurology, Memory and Aging Center, University of California San Francisco, San Francisco, CA, USA.
  • Kriegstein AR; Department of Genetics and Complex Diseases, T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
  • Huang EJ; Howard Hughes Medical Institute, Boston, MA, USA.
Nature ; 588(7838): 459-465, 2020 12.
Article em En | MEDLINE | ID: mdl-32866962
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microglia / Proteinopatias TDP-43 / Progranulinas / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Nature Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microglia / Proteinopatias TDP-43 / Progranulinas / Neurônios Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Nature Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos