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DNA methylation study of Huntington's disease and motor progression in patients and in animal models.
Lu, Ake T; Narayan, Pritika; Grant, Matthew J; Langfelder, Peter; Wang, Nan; Kwak, Seung; Wilkinson, Hilary; Chen, Richard Z; Chen, Jian; Simon Bawden, C; Rudiger, Skye R; Ciosi, Marc; Chatzi, Afroditi; Maxwell, Alastair; Hore, Timothy A; Aaronson, Jeff; Rosinski, Jim; Preiss, Alicia; Vogt, Thomas F; Coppola, Giovanni; Monckton, Darren; Snell, Russell G; William Yang, X; Horvath, Steve.
Afiliação
  • Lu AT; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Narayan P; Applied Translational Genetics Group, School of Biological Sciences, Centre for Brain Research, The University of Auckland, Auckland, 1010, New Zealand.
  • Grant MJ; Applied Translational Genetics Group, School of Biological Sciences, Centre for Brain Research, The University of Auckland, Auckland, 1010, New Zealand.
  • Langfelder P; Center for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA), Los Angeles, CA, 90095, USA.
  • Wang N; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA.
  • Kwak S; Center for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA), Los Angeles, CA, 90095, USA.
  • Wilkinson H; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA.
  • Chen RZ; CHDI Management/CHDI Foundation, Princeton, NJ, 08540, USA.
  • Chen J; CHDI Management/CHDI Foundation, Princeton, NJ, 08540, USA.
  • Simon Bawden C; CHDI Management/CHDI Foundation, Princeton, NJ, 08540, USA.
  • Rudiger SR; CHDI Management/CHDI Foundation, Princeton, NJ, 08540, USA.
  • Ciosi M; Livestock and Farming Systems, South Australian Research and Development Institute, Roseworthy, SA, 5371, Australia.
  • Chatzi A; Livestock and Farming Systems, South Australian Research and Development Institute, Roseworthy, SA, 5371, Australia.
  • Maxwell A; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK.
  • Hore TA; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK.
  • Aaronson J; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK.
  • Rosinski J; Department of Anatomy, University of Otago, Dunedin, 9016, New Zealand.
  • Preiss A; CHDI Management/CHDI Foundation, Princeton, NJ, 08540, USA.
  • Vogt TF; CHDI Management/CHDI Foundation, Princeton, NJ, 08540, USA.
  • Coppola G; CHDI Management/CHDI Foundation, Princeton, NJ, 08540, USA.
  • Monckton D; CHDI Management/CHDI Foundation, Princeton, NJ, 08540, USA.
  • Snell RG; Center for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA), Los Angeles, CA, 90095, USA.
  • William Yang X; Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA.
  • Horvath S; Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, UK.
Nat Commun ; 11(1): 4529, 2020 09 10.
Article em En | MEDLINE | ID: mdl-32913184
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Huntington / Metilação de DNA / Epigênese Genética / Proteína Huntingtina Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Aged80 Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Huntington / Metilação de DNA / Epigênese Genética / Proteína Huntingtina Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Aged80 Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos