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Granulomas and nongranulomatous nodules after filler injection: Different complications require different treatments.
Modarressi, Ali; Nizet, Christophe; Lombardi, Tommaso.
Afiliação
  • Modarressi A; Division of Plastic, Reconstructive & Aesthetic Surgery, Department of Surgery, Geneva University Hospitals, 4 Rue Gabrielle-Perret-Gentil, 1211 Geneva, Switzerland. Electronic address: ali.modarressi@hcuge.ch.
  • Nizet C; Division of Plastic, Reconstructive & Aesthetic Surgery, Department of Surgery, Geneva University Hospitals, 4 Rue Gabrielle-Perret-Gentil, 1211 Geneva, Switzerland.
  • Lombardi T; Laboratory of Histopathology, Division of Stomatology, University of Geneva, Geneva, Switzerland.
J Plast Reconstr Aesthet Surg ; 73(11): 2010-2015, 2020 Nov.
Article em En | MEDLINE | ID: mdl-32928687
ABSTRACT
Dermal fillers are widely used for facial rejuvenation and reconstruction and present fewer risks than surgical approaches. Nevertheless, several complications may occur, including nodule formation. A nodule is a clinical sign corresponding to different etiologies, such as overcorrection, infection, allergic reaction, or granuloma. However, their treatment represents a diagnostic challenge. We present a retrospective review of 26 consecutive patients who underwent a biopsy for facial nodule formation more than 3 months after filler injections, to determine the diagnosis of the nodule and type of filler used. All patients were women (mean age, 57.8 years). Some patients suffered from different localizations lip, 14 cases; nasolabial folds, 6; cheeks, 5; infraorbital region, 5; the glabella, 2; the temporal region, 1; and chin, 1 case. Only 5 (19.2%) patients knew the type of filler used, and in another 4 cases, the injector was able to provide some information. In 65.4% of cases, the filler type was unknown. Histopathological analysis revealed a "granulomatous" nodule in 30 sites and a "non-granulomatous" nodule in 4 cases. Concerning the type of filler, 5 different histopathological patterns were found. Our results demonstrate that a clinical history and histopathological analysis whether to confirm or not to confirm the diagnosis of granuloma and to identify the type of filler are essential tools to achieve an accurate diagnosis of the problem-oriented treatment of nodules after dermal filler injections. We propose an algorithm for the management of nodules after filler injection.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações Pós-Operatórias / Biópsia / Técnicas Cosméticas / Procedimentos de Cirurgia Plástica / Preenchedores Dérmicos Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies Limite: Female / Humans / Middle aged Idioma: En Revista: J Plast Reconstr Aesthet Surg Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações Pós-Operatórias / Biópsia / Técnicas Cosméticas / Procedimentos de Cirurgia Plástica / Preenchedores Dérmicos Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies Limite: Female / Humans / Middle aged Idioma: En Revista: J Plast Reconstr Aesthet Surg Ano de publicação: 2020 Tipo de documento: Article