A study of the immune infiltrate and patient outcomes in esophageal cancer.

Conroy, Melissa J; Kennedy, Susan A; Doyle, Suzanne L; Hayes, Brian; Kavanagh, Maria; van der Stok, Eric P; O'Sullivan, Katie; Cathcart, Mary-Clare; Reynolds, John V; Lysaght, Joanne

Conroy, Melissa J; Kennedy, Susan A; Doyle, Suzanne L; Hayes, Brian; Kavanagh, Maria; van der Stok, Eric P; O'Sullivan, Katie; Cathcart, Mary-Clare; Reynolds, John V; Lysaght, Joanne.

Afiliação

Conroy MJ; Department of Surgery, Cancer Immunology and Immunotherapy Group, Trinity Translational Medicine Institute, Trinity College Dublin, St James's Hospital, Dublin, Ireland.
Kennedy SA; Department of Surgery, Cancer Immunology and Immunotherapy Group, Trinity Translational Medicine Institute, Trinity College Dublin, St James's Hospital, Dublin, Ireland.
Doyle SL; School of Biological Sciences, Dublin Institute of Technology, Ireland.
Hayes B; Department of Histopathology, Cork University Hospital and Department of Pathology, University College Cork, Ireland.
Kavanagh M; Department of Surgery, Cancer Immunology and Immunotherapy Group, Trinity Translational Medicine Institute, Trinity College Dublin, St James's Hospital, Dublin, Ireland.
van der Stok EP; Department of Surgical Oncology, Erasmus MC Cancer Institute, The Netherlands.
O'Sullivan K; Department of Surgery, Cancer Immunology and Immunotherapy Group, Trinity Translational Medicine Institute, Trinity College Dublin, St James's Hospital, Dublin, Ireland.
Cathcart MC; Department of Surgery, Cancer Immunology and Immunotherapy Group, Trinity Translational Medicine Institute, Trinity College Dublin, St James's Hospital, Dublin, Ireland.
Reynolds JV; National Esophageal and Gastric Centre, St. James's Hospital, Dublin, Ireland.
Lysaght J; Department of Surgery, Cancer Immunology and Immunotherapy Group, Trinity Translational Medicine Institute, Trinity College Dublin, St James's Hospital, Dublin, Ireland.

Carcinogenesis ; 42(3): 395-404, 2021 04 17.

Article em En | MEDLINE | ID: mdl-32940666

Assuntos

Adenocarcinoma/imunologia; Biomarcadores Tumorais/análise; Neoplasias Esofágicas/imunologia; Carcinoma de Células Escamosas do Esôfago/imunologia; Linfócitos do Interstício Tumoral/metabolismo; Linfócitos T Citotóxicos/metabolismo; Adenocarcinoma/diagnóstico; Adenocarcinoma/patologia; Adenocarcinoma/cirurgia; Adulto; Idoso; Idoso de 80 Anos ou mais; Biomarcadores Tumorais/metabolismo; Degranulação Celular/imunologia; Diagnóstico Diferencial; Neoplasias Esofágicas/diagnóstico; Neoplasias Esofágicas/patologia; Neoplasias Esofágicas/cirurgia; Carcinoma de Células Escamosas do Esôfago/diagnóstico; Carcinoma de Células Escamosas do Esôfago/patologia; Carcinoma de Células Escamosas do Esôfago/cirurgia; Esofagectomia; Esôfago/imunologia; Esôfago/patologia; Esôfago/cirurgia; Feminino; Humanos; Memória Imunológica; Imunofenotipagem; Antígenos Comuns de Leucócito/análise; Antígenos Comuns de Leucócito/metabolismo; Linfócitos do Interstício Tumoral/imunologia; Masculino; Pessoa de Meia-Idade; Prognóstico; Linfócitos T Citotóxicos/imunologia; Análise Serial de Tecidos; Microambiente Tumoral/imunologia

Palavras-chave

CD8+ T cells; esophageal cancer; immune contexture; tumor microenvironment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Linfócitos T Citotóxicos / Adenocarcinoma / Biomarcadores Tumorais / Linfócitos do Interstício Tumoral / Carcinoma de Células Escamosas do Esôfago Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Aged80 Idioma: En Revista: Carcinogenesis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Irlanda

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