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The marine compound and elongation factor 1A1 inhibitor, didemnin B, provides benefit in western diet-induced non-alcoholic fatty liver disease.
Wilson, Rachel B; Chen, Yun Jin; Sutherland, Brian G; Sawyez, Cynthia G; Zhang, Richard; Woolnough, Taylor; Hetherington, Alexandra M; Peters, Kia M; Patel, Krisha; Kennelly, John P; Leonard, Kelly-Ann; Schuurman, Meg; Jacobs, René L; Wang, Rennian; Borradaile, Nica M.
Afiliação
  • Wilson RB; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
  • Chen YJ; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
  • Sutherland BG; Robarts Research Institute, Western University, London, ON, Canada.
  • Sawyez CG; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
  • Zhang R; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
  • Woolnough T; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
  • Hetherington AM; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
  • Peters KM; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
  • Patel K; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
  • Kennelly JP; Group on the Molecular and Cell Biology of Lipids, Department of Agricultural, Food and Nutrition Science, University of Alberta, Edmonton, AB, Canada.
  • Leonard KA; Group on the Molecular and Cell Biology of Lipids, Department of Agricultural, Food and Nutrition Science, University of Alberta, Edmonton, AB, Canada.
  • Schuurman M; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
  • Jacobs RL; Group on the Molecular and Cell Biology of Lipids, Department of Agricultural, Food and Nutrition Science, University of Alberta, Edmonton, AB, Canada.
  • Wang R; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
  • Borradaile NM; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. Electronic address: nica.borradaile@schulich.uwo.ca.
Pharmacol Res ; 161: 105208, 2020 11.
Article em En | MEDLINE | ID: mdl-32977024
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Síntese de Proteínas / Fator 1 de Elongação de Peptídeos / Depsipeptídeos / Hepatopatia Gordurosa não Alcoólica / Dieta Ocidental / Fígado / Cirrose Hepática Tipo de estudo: Etiology_studies / Prognostic_studies Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Síntese de Proteínas / Fator 1 de Elongação de Peptídeos / Depsipeptídeos / Hepatopatia Gordurosa não Alcoólica / Dieta Ocidental / Fígado / Cirrose Hepática Tipo de estudo: Etiology_studies / Prognostic_studies Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá