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Masking terminal neo-epitopes of linear peptides through glycosylation favours immune responses towards core epitopes producing parental protein bound antibodies.
Pon, Robert; Marcil, Anne; Chen, Wangxue; Gadoury, Christine; Williams, Dean; Chan, Kenneth; Zhou, Hongyan; Ponce, Amalia; Paquet, Eric; Gurnani, Komal; Chattopadhyay, Anindita; Zou, Wei.
Afiliação
  • Pon R; Human Health Therapeutics Research Center, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, K1A 0R6, Canada.
  • Marcil A; Human Health Therapeutics Research Center, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, K1A 0R6, Canada.
  • Chen W; Human Health Therapeutics Research Center, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, K1A 0R6, Canada.
  • Gadoury C; Human Health Therapeutics Research Center, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, K1A 0R6, Canada.
  • Williams D; Human Health Therapeutics Research Center, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, K1A 0R6, Canada.
  • Chan K; Human Health Therapeutics Research Center, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, K1A 0R6, Canada.
  • Zhou H; Human Health Therapeutics Research Center, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, K1A 0R6, Canada.
  • Ponce A; Human Health Therapeutics Research Center, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, K1A 0R6, Canada.
  • Paquet E; Digital Technology Research Center, National Research Council of Canada, 1200 Montreal Road, Ottawa, ON, K1A 0R6, Canada.
  • Gurnani K; Human Health Therapeutics Research Center, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, K1A 0R6, Canada.
  • Chattopadhyay A; Human Health Therapeutics Research Center, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, K1A 0R6, Canada.
  • Zou W; Human Health Therapeutics Research Center, National Research Council of Canada, 100 Sussex Drive, Ottawa, ON, K1A 0R6, Canada. wei.zou@nrc-cnrc.gc.ca.
Sci Rep ; 10(1): 18497, 2020 10 28.
Article em En | MEDLINE | ID: mdl-33116268

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais / Glicoproteínas de Hemaglutininação de Vírus da Influenza / Anticorpos Antivirais / Epitopos / Neuraminidase Limite: Animals / Female / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais / Glicoproteínas de Hemaglutininação de Vírus da Influenza / Anticorpos Antivirais / Epitopos / Neuraminidase Limite: Animals / Female / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Canadá