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Robust folding of a de novo designed ideal protein even with most of the core mutated to valine.
Koga, Rie; Yamamoto, Mami; Kosugi, Takahiro; Kobayashi, Naohiro; Sugiki, Toshihiko; Fujiwara, Toshimichi; Koga, Nobuyasu.
Afiliação
  • Koga R; Protein Design Group, Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, Okazaki, Aichi 444-8585, Japan; riekoga@ims.ac.jp nkoga@ims.ac.jp.
  • Yamamoto M; Department of Structural Molecular Science, School of Physical Sciences, The Graduate University for Advanced Studies, SOKENDAI, Hayama, Kanagawa 240-0193, Japan.
  • Kosugi T; Protein Design Group, Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, Okazaki, Aichi 444-8585, Japan.
  • Kobayashi N; Department of Structural Molecular Science, School of Physical Sciences, The Graduate University for Advanced Studies, SOKENDAI, Hayama, Kanagawa 240-0193, Japan.
  • Sugiki T; Research Center of Integrative Molecular Systems, Institute for Molecular Science, National Institutes of Natural Sciences, Okazaki, Aichi 444-8585, Japan.
  • Fujiwara T; Laboratory of Molecular Biophysics, Institute for Protein Research, Osaka University, Suita, Osaka 565-0871, Japan.
  • Koga N; RIKEN Spring-8 Center, RIKEN, Yokohama, Kanagawa 230-0045, Japan.
Proc Natl Acad Sci U S A ; 117(49): 31149-31156, 2020 12 08.
Article em En | MEDLINE | ID: mdl-33229587
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Conformação Proteica / Engenharia de Proteínas / Proteínas / Dobramento de Proteína Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Conformação Proteica / Engenharia de Proteínas / Proteínas / Dobramento de Proteína Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article