Photo-Enhanced CRISPR/Cas9 System Enables Robust PD-L1 Gene Disruption in Cancer Cells and Cancer Stem-Like Cells for Efficient Cancer Immunotherapy.

Zhao, Liang; Luo, Yingli; Huang, Qiaoyi; Cao, Ziyang; Yang, Xianzhu

Zhao, Liang; Luo, Yingli; Huang, Qiaoyi; Cao, Ziyang; Yang, Xianzhu.

Afiliação

Zhao L; Guangzhou First People's Hospital, School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou, 510006, P. R. China.
Luo Y; Key Laboratory of Biomedical Engineering of Guangdong Province and National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou, 510006, P. R. China.
Huang Q; Guangzhou First People's Hospital, School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou, 510006, P. R. China.
Cao Z; Guangzhou First People's Hospital, School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou, 510006, P. R. China.
Yang X; Guangzhou First People's Hospital, School of Biomedical Sciences and Engineering, South China University of Technology, Guangzhou, 510006, P. R. China.

Small ; : e2004879, 2020 Dec 02.

Article em En | MEDLINE | ID: mdl-33289336

Palavras-chave

PD1/PDL1 blockade; cancer immunotherapy; cancer stemlike cells; photoactivated selfdegradable nanocomplex; photoswitched CRISPR/Cas9 system

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Small Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2020 Tipo de documento: Article

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