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Purpurin binding interacts with LHPP protein that inhibits PI3K/AKT phosphorylation and induces apoptosis in colon cancer cells HCT-116.
Li, Zhiwen; Zhou, Xu; Zhu, Huaqiang; Song, Xie; Gao, Hengjun; Niu, Zheyu; Lu, Jun.
Afiliação
  • Li Z; Department of Colorectal and Anal Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan City, Shandong Province, China.
  • Zhou X; Department of Hepatobiliary Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan City, Shandong Province, China.
  • Zhu H; Department of Hepatobiliary Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan City, Shandong Province, China.
  • Song X; Department of Hepatobiliary Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan City, Shandong Province, China.
  • Gao H; Department of Hepatobiliary Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan City, Shandong Province, China.
  • Niu Z; Department of Hepatobiliary Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan City, Shandong Province, China.
  • Lu J; Department of Hepatobiliary Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan City, Shandong Province, China.
J Biochem Mol Toxicol ; 35(3): e22665, 2021 Mar.
Article em En | MEDLINE | ID: mdl-33368780
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Antraquinonas / Apoptose / Neoplasias do Colo / Fosfatidilinositol 3-Quinases / Pirofosfatase Inorgânica / Proteínas Proto-Oncogênicas c-akt Limite: Humans Idioma: En Revista: J Biochem Mol Toxicol Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA / TOXICOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Antraquinonas / Apoptose / Neoplasias do Colo / Fosfatidilinositol 3-Quinases / Pirofosfatase Inorgânica / Proteínas Proto-Oncogênicas c-akt Limite: Humans Idioma: En Revista: J Biochem Mol Toxicol Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA / TOXICOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China