Sulfadoxine-pyrimethamine parasitological efficacy against Plasmodium falciparum among pregnant women and molecular markers of resistance in Zambia: an observational cohort study.

Chaponda, Enesia Banda; Mharakurwa, Sungano; Michelo, Charles; Bruce, Jane; Chandramoha, Daniel; Matthew Chico, R

Chaponda, Enesia Banda; Mharakurwa, Sungano; Michelo, Charles; Bruce, Jane; Chandramoha, Daniel; Matthew Chico, R.

Afiliação

Chaponda EB; Department of Biological Sciences, University of Zambia, Lusaka, Zambia. enesia.chaponda@gmail.com.
Mharakurwa S; Africa University, Fairview Road, Old Mutare, Mutare, Zimbabwe.
Michelo C; Department of Epidemiology, School of Public Health, University of Zambia, Lusaka, Zambia.
Bruce J; Strategic Centre for Health Systems Metrics and Evaluations, School of Public Health, University of Zambia, Lusaka, Zambia.
Chandramoha D; Department of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.
Matthew Chico R; Department of Disease Control, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.

Malar J ; 20(1): 61, 2021 Jan 22.

Article em En | MEDLINE | ID: mdl-33482823

Assuntos

Antimaláricos/uso terapêutico; Malária Falciparum/tratamento farmacológico; Plasmodium falciparum/efeitos dos fármacos; Pirimetamina/uso terapêutico; Sulfadoxina/uso terapêutico; Adulto; Estudos de Coortes; Combinação de Medicamentos; Feminino; Marcadores Genéticos/genética; Humanos; Malária Falciparum/epidemiologia; Mutação; Parasitemia/tratamento farmacológico; Plasmodium falciparum/genética; Gravidez; Gestantes; Prevalência; Adulto Jovem; Zâmbia/epidemiologia

Palavras-chave

DHFR triple mutation (asn-108 + ile-51 + arg-59); DHPS double mutation (gly-437 + glu-540); Intermittent preventive treatment of malaria in pregnancy (IPTp); Quintuple mutation (DHFR triple + DHPS double); Sextuple mutation (DHFR triple + DHPS double + arg-581); Sulfadoxine-pyrimethamine (SP)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plasmodium falciparum / Pirimetamina / Sulfadoxina / Malária Falciparum / Antimaláricos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Pregnancy País/Região como assunto: Africa Idioma: En Revista: Malar J Assunto da revista: MEDICINA TROPICAL Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Zâmbia

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