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Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD.
Li, Xiuying; Noell, Guillaume; Tabib, Tracy; Gregory, Alyssa D; Trejo Bittar, Humberto E; Vats, Ravi; Kaminski, Tomasz W; Sembrat, John; Snyder, Mark E; Chandra, Divay; Chen, Kong; Zou, Chunbin; Zhang, Yingze; Sundd, Prithu; McDyer, John F; Sciurba, Frank; Rojas, Mauricio; Lafyatis, Robert; Shapiro, Steve D; Faner, Rosa; Nyunoya, Toru.
Afiliação
  • Li X; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
  • Noell G; VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.
  • Tabib T; Centro Investigación Biomedica en Red (CIBERES), Institut D'investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.
  • Gregory AD; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
  • Trejo Bittar HE; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
  • Vats R; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA.
  • Kaminski TW; Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  • Sembrat J; Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  • Snyder ME; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
  • Chandra D; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
  • Chen K; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
  • Zou C; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
  • Zhang Y; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
  • Sundd P; VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.
  • McDyer JF; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
  • Sciurba F; Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
  • Rojas M; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
  • Lafyatis R; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
  • Shapiro SD; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
  • Faner R; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
  • Nyunoya T; Department of Medicine, University of Pittsburgh, NW628 UPMC Montefiore, 3459 Fifth Avenue, Pittsburgh, PA, 15213, USA.
Respir Res ; 22(1): 100, 2021 Apr 06.
Article em En | MEDLINE | ID: mdl-33823868

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Proteínas de Ligação a RNA / Análise de Sequência de RNA / Proteína 5 de Ligação a Fator de Crescimento Semelhante à Insulina / Doença Pulmonar Obstrutiva Crônica / Transcriptoma / Pulmão Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Respir Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Proteínas de Ligação a RNA / Análise de Sequência de RNA / Proteína 5 de Ligação a Fator de Crescimento Semelhante à Insulina / Doença Pulmonar Obstrutiva Crônica / Transcriptoma / Pulmão Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Respir Res Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos