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Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19.
Theobald, Sebastian J; Simonis, Alexander; Georgomanolis, Theodoros; Kreer, Christoph; Zehner, Matthias; Eisfeld, Hannah S; Albert, Marie-Christine; Chhen, Jason; Motameny, Susanne; Erger, Florian; Fischer, Julia; Malin, Jakob J; Gräb, Jessica; Winter, Sandra; Pouikli, Andromachi; David, Friederike; Böll, Boris; Koehler, Philipp; Vanshylla, Kanika; Gruell, Henning; Suárez, Isabelle; Hallek, Michael; Fätkenheuer, Gerd; Jung, Norma; Cornely, Oliver A; Lehmann, Clara; Tessarz, Peter; Altmüller, Janine; Nürnberg, Peter; Kashkar, Hamid; Klein, Florian; Koch, Manuel; Rybniker, Jan.
Afiliação
  • Theobald SJ; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Simonis A; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Georgomanolis T; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Kreer C; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Zehner M; Faculty of Medicine and University Hospital of Cologne, Cologne Center for Genomics (CCG), University of Cologne, Cologne, Germany.
  • Eisfeld HS; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Albert MC; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Chhen J; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Motameny S; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Erger F; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
  • Fischer J; Institute for Medical Microbiology, Immunology and Hygiene (IMMIH), University of Cologne, Cologne, Germany.
  • Malin JJ; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Gräb J; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Winter S; Faculty of Medicine and University Hospital of Cologne, Cologne Center for Genomics (CCG), University of Cologne, Cologne, Germany.
  • Pouikli A; Faculty of Medicine and University Hospital of Cologne, Cologne Center for Genomics (CCG), University of Cologne, Cologne, Germany.
  • David F; Faculty of Medicine, Institute of Human Genetics, University Hospital Cologne, Cologne, Germany.
  • Böll B; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Koehler P; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Vanshylla K; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany.
  • Gruell H; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Suárez I; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Hallek M; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Fätkenheuer G; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Jung N; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Cornely OA; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Lehmann C; Max Planck Research Group "Chromatin and Ageing", Max Planck Institute for Biology of Ageing, Cologne, Germany.
  • Tessarz P; Faculty of Medicine and University Hospital of Cologne, Cologne Center for Genomics (CCG), University of Cologne, Cologne, Germany.
  • Altmüller J; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Nürnberg P; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Kashkar H; Faculty of Medicine and University Hospital of Cologne, Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.
  • Klein F; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
  • Koch M; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
  • Rybniker J; Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.
EMBO Mol Med ; 13(8): e14150, 2021 08 09.
Article em En | MEDLINE | ID: mdl-34133077

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteína da Espícula de Coronavírus / COVID-19 Limite: Humans Idioma: En Revista: EMBO Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteína da Espícula de Coronavírus / COVID-19 Limite: Humans Idioma: En Revista: EMBO Mol Med Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha