Drug discovery in the era of cryo-electron microscopy.

Robertson, Michael J; Meyerowitz, Justin G; Skiniotis, Georgios

Robertson, Michael J; Meyerowitz, Justin G; Skiniotis, Georgios.

Afiliação

Robertson MJ; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
Meyerowitz JG; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA; Department of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA, USA.
Skiniotis G; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: yiorgo@stanford.edu.

Trends Biochem Sci ; 47(2): 124-135, 2022 02.

Article em En | MEDLINE | ID: mdl-34281791

Assuntos

Microscopia Crioeletrônica; Descoberta de Drogas; Microscopia Crioeletrônica/métodos; Cristalografia por Raios X; Descoberta de Drogas/métodos

Palavras-chave

biologics; cryo-electron microscopy; pharmacology; single-particle analysis; small molecule; structure-based drug discovery

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microscopia Crioeletrônica / Descoberta de Drogas Idioma: En Revista: Trends Biochem Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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