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A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus-vulnerable site.
Onodera, Taishi; Kita, Shunsuke; Adachi, Yu; Moriyama, Saya; Sato, Akihiko; Nomura, Takao; Sakakibara, Shuhei; Inoue, Takeshi; Tadokoro, Takashi; Anraku, Yuki; Yumoto, Kohei; Tian, Cong; Fukuhara, Hideo; Sasaki, Michihito; Orba, Yasuko; Shiwa, Nozomi; Iwata, Naoko; Nagata, Noriyo; Suzuki, Tateki; Sasaki, Jiei; Sekizuka, Tsuyoshi; Tonouchi, Keisuke; Sun, Lin; Fukushi, Shuetsu; Satofuka, Hiroyuki; Kazuki, Yasuhiro; Oshimura, Mitsuo; Kurosaki, Tomohiro; Kuroda, Makoto; Matsuura, Yoshiharu; Suzuki, Tadaki; Sawa, Hirofumi; Hashiguchi, Takao; Maenaka, Katsumi; Takahashi, Yoshimasa.
Afiliação
  • Onodera T; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
  • Kita S; Laboratory of Biomolecular Science, and Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
  • Adachi Y; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
  • Moriyama S; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
  • Sato A; Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan; Drug Discovery & Disease Research Laboratory, Shionogi & Co., Ltd., Osaka 561-0825, Japan.
  • Nomura T; Laboratory of Biomolecular Science, and Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
  • Sakakibara S; Laboratory of Immune Regulation, WPI Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.
  • Inoue T; Laboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.
  • Tadokoro T; Laboratory of Biomolecular Science, and Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
  • Anraku Y; Laboratory of Biomolecular Science, and Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
  • Yumoto K; Laboratory of Biomolecular Science, and Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
  • Tian C; Laboratory of Biomolecular Science, and Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
  • Fukuhara H; Laboratory of Biomolecular Science, and Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan; Global Station for Biosurfaces and Drug Discovery, Hokkaido University, Sapporo 060-0812, Japan.
  • Sasaki M; Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
  • Orba Y; Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
  • Shiwa N; Department of Pathology, National Institute of Infectious Diseases, Tokyo 208-0011, Japan.
  • Iwata N; Department of Pathology, National Institute of Infectious Diseases, Tokyo 208-0011, Japan.
  • Nagata N; Department of Pathology, National Institute of Infectious Diseases, Tokyo 208-0011, Japan.
  • Suzuki T; Department of Virology, Faculty of Medicine, Kyushu University, Fukuoka 812-8582, Japan.
  • Sasaki J; Department of Virology, Faculty of Medicine, Kyushu University, Fukuoka 812-8582, Japan.
  • Sekizuka T; Pathogen Genomic Center, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
  • Tonouchi K; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo 162-8640, Japan; Department of Life Science and Medical Bioscience, Waseda University, Tokyo 162-8480, Japan.
  • Sun L; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
  • Fukushi S; Department of Virology I, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
  • Satofuka H; Chromosome Engineering Research Center, Tottori University, Tottori 683-8503, Japan.
  • Kazuki Y; Chromosome Engineering Research Center, Tottori University, Tottori 683-8503, Japan; Division of Genome and Cellular Functions, Department of Molecular and Cellular Biology, School of Life Science, Faculty of Medicine, Tottori University, Tottori 683-8503, Japan.
  • Oshimura M; Trans Chromosomics Inc., Tottori 683-8503, Japan.
  • Kurosaki T; Laboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Osaka 565-0871, Japan.
  • Kuroda M; Pathogen Genomic Center, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
  • Matsuura Y; Laboratory of Virus Control, Center for Infectious Diseases Education and Research, Osaka University, Osaka 565-0871, Japan.
  • Suzuki T; Department of Pathology, National Institute of Infectious Diseases, Tokyo 208-0011, Japan.
  • Sawa H; Division of Molecular Pathobiology, Research Center for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
  • Hashiguchi T; Department of Virology, Faculty of Medicine, Kyushu University, Fukuoka 812-8582, Japan; Laboratory of Medical Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
  • Maenaka K; Laboratory of Biomolecular Science, and Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan; Global Station for Biosurfaces and Drug Discovery, Hokkaido University, Sapporo 060-0812, Japan. Electronic address: maenaka@
  • Takahashi Y; Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo 162-8640, Japan. Electronic address: ytakahas@niid.go.jp.
Immunity ; 54(10): 2385-2398.e10, 2021 10 12.
Article em En | MEDLINE | ID: mdl-34508662
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reações Cruzadas / Anticorpos Amplamente Neutralizantes / SARS-CoV-2 Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reações Cruzadas / Anticorpos Amplamente Neutralizantes / SARS-CoV-2 Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão