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The Natural Products Atlas 2.0: a database of microbially-derived natural products.
van Santen, Jeffrey A; Poynton, Ella F; Iskakova, Dasha; McMann, Emily; Alsup, Tyler A; Clark, Trevor N; Fergusson, Claire H; Fewer, David P; Hughes, Alison H; McCadden, Caitlin A; Parra, Jonathan; Soldatou, Sylvia; Rudolf, Jeffrey D; Janssen, Elisabeth M-L; Duncan, Katherine R; Linington, Roger G.
Afiliação
  • van Santen JA; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.
  • Poynton EF; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.
  • Iskakova D; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.
  • McMann E; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.
  • Alsup TA; Department of Chemistry, University of Florida, Gainesville, FL 32611, USA.
  • Clark TN; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.
  • Fergusson CH; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.
  • Fewer DP; Department of Microbiology, University of Helsinki, 00014 Helsinki, Finland.
  • Hughes AH; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, Glasgow G4 0RE, UK.
  • McCadden CA; Department of Chemistry, University of Florida, Gainesville, FL 32611, USA.
  • Parra J; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, Glasgow G4 0RE, UK.
  • Soldatou S; Marine Biodiscovery Centre, Department of Chemistry, University of Aberdeen, Aberdeen AB24 3UE, UK.
  • Rudolf JD; Department of Chemistry, University of Florida, Gainesville, FL 32611, USA.
  • Janssen EM; Department of Environmental Chemistry, Swiss Federal Institute of Aquatic Science and Technology (Eawag), 8600 Duebendorf, Switzerland.
  • Duncan KR; Strathclyde Institute of Pharmacy and Biomedical Science, University of Strathclyde, Glasgow G4 0RE, UK.
  • Linington RG; Department of Chemistry, Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.
Nucleic Acids Res ; 50(D1): D1317-D1323, 2022 01 07.
Article em En | MEDLINE | ID: mdl-34718710
Within the natural products field there is an increasing emphasis on the study of compounds from microbial sources. This has been fuelled by interest in the central role that microorganisms play in mediating both interspecies interactions and host-microbe relationships. To support the study of natural products chemistry produced by microorganisms we released the Natural Products Atlas, a database of known microbial natural products structures, in 2019. This paper reports the release of a new version of the database which includes a full RESTful application programming interface (API), a new website framework, and an expanded database that includes 8128 new compounds, bringing the total to 32 552. In addition to these structural and content changes we have added full taxonomic descriptions for all microbial taxa and have added chemical ontology terms from both NP Classifier and ClassyFire. We have also performed manual curation to review all entries with incomplete configurational assignments and have integrated data from external resources, including CyanoMetDB. Finally, we have improved the user experience by updating the Overview dashboard and creating a dashboard for taxonomic origin. The database can be accessed via the new interactive website at https://www.npatlas.org.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Software / Bases de Dados Factuais / Interações entre Hospedeiro e Microrganismos Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Software / Bases de Dados Factuais / Interações entre Hospedeiro e Microrganismos Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá