Hepatocyte-derived exosomal miR-27a activateshepatic stellate cells through the inhibitionof PINK1-mediated mitophagy in MAFLD.

Luo, Xin; Xu, Zi-Xin; Wu, Jun-Cheng; Luo, Sheng-Zheng; Xu, Ming-Yi

Luo, Xin; Xu, Zi-Xin; Wu, Jun-Cheng; Luo, Sheng-Zheng; Xu, Ming-Yi.

Afiliação

Luo X; Department of Gastroenterology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Xu ZX; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080 China.
Wu JC; Department of Gastroenterology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China.
Luo SZ; Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080 China.
Xu MY; Departments of Gastroenterology, The Third Affiliated Hospital of Soochow University, Changzhou, 213000 Jiangsu Province, China.

Mol Ther Nucleic Acids ; 26: 1241-1254, 2021 Dec 03.

Article em En | MEDLINE | ID: mdl-34853724

Palavras-chave

HSC; MAFLD; PINK1; PTEN-induced putative protein kinase 1; exosomes; hepatic stellate cell; metabolic-associated fatty liver disease; miR27a; microRNA-27a; mitophagy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Mol Ther Nucleic Acids Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China

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