Rheumatoid arthritis is a risk factor for refracture in patients with fragility fractures.
Mod Rheumatol
; 32(6): 1017-1022, 2022 Oct 15.
Article
em En
| MEDLINE
| ID: mdl-34865103
ABSTRACT
OBJECTIVES:
To determine whether patients with rheumatoid arthritis (RA) who have had fragility fractures are at an increased risk of refractures.METHODS:
Patients with fragility fractures who were treated surgically at 10 hospitals from 2008 to 2017 and who underwent follow-up for >24 months were either categorized into a group comprising patients with RA or a group comprising patients without RA (controls). The groups were matched 11 by propensity score matching. Accordingly, 240 matched participants were included in this study. The primary outcome was the refracture rate in patients with RA as compared to in the controls. Multivariable analyses were also conducted on patients with RA to evaluate the odds ratios (ORs) for the refracture rates.RESULTS:
Patients with RA were significantly associated with increased rates of refractures during the first 24 months (OR 2.714, 95% confidence interval [95% CI] 1.015-7.255; p = 0.040). Multivariable analyses revealed a significant association between increased refracture rates and long-term RA (OR 6.308, 95% CI 1.195-33.292; p = 0.030).CONCLUSIONS:
Patients with RA who have experienced fragility fractures are at an increased risk of refractures. Long-term RA is a substantial risk factor for refractures.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artrite Reumatoide
/
Fraturas Ósseas
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Mod Rheumatol
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Japão