Multiphysics Modelling and Simulation of Thrombolysis via Activated Platelet-Targeted Nanomedicine.

Gu, Boram; Huang, Yu; Manchester, Emily Louise; Hughes, Alun D; Thom, Simon A McG; Chen, Rongjun; Xu, Xiao Yun

Gu, Boram; Huang, Yu; Manchester, Emily Louise; Hughes, Alun D; Thom, Simon A McG; Chen, Rongjun; Xu, Xiao Yun.

Afiliação

Gu B; Department of Chemical Engineering, Imperial College London, South Kensington Campus, London, UK.
Huang Y; School of Chemical Engineering, Chonnam National University, Gwangju, Republic of Korea.
Manchester EL; Department of Chemical Engineering, Imperial College London, South Kensington Campus, London, UK.
Hughes AD; Department of Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Jiao Tong University School of Medicine, 600 Yi Shan Road, Shanghai, China.
Thom SAM; Department of Chemical Engineering, Imperial College London, South Kensington Campus, London, UK.
Chen R; Institute of Cardiovascular Science, University College London, London, UK.
Xu XY; MRC Unit for Lifelong Health and Ageing at University College London, London, UK.

Pharm Res ; 39(1): 41-56, 2022 Jan.

Article em En | MEDLINE | ID: mdl-35044591

Assuntos

Fibrinólise; Ativador de Plasminogênio Tecidual; Fibrinolíticos/farmacologia; Nanomedicina; Terapia Trombolítica/métodos; Ativador de Plasminogênio Tecidual/farmacologia; Ativador de Plasminogênio Tecidual/uso terapêutico

Palavras-chave

multiphysics modelling; pharmacodynamics; pharmacokinetics; targeted drug delivery; thrombolysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ativador de Plasminogênio Tecidual / Fibrinólise Tipo de estudo: Risk_factors_studies Idioma: En Revista: Pharm Res Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido

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