Synthesis and Evaluation of 1,3,5-Triaryl-2-Pyrazoline Derivatives as Potent Dual Inhibitors of Urease and &#945;-Glucosidase Together with Their Cytotoxic, Molecular Modeling and Drug-Likeness Studies.

Mehmood, Rabia; Sadiq, Amina; Alsantali, Reem I; Mughal, Ehsan Ullah; Alsharif, Meshari A; Naeem, Nafeesa; Javid, Asif; Al-Rooqi, Munirah M; Chaudhry, Gul-E-Saba; Ahmed, Saleh A

Synthesis and Evaluation of 1,3,5-Triaryl-2-Pyrazoline Derivatives as Potent Dual Inhibitors of Urease and α-Glucosidase Together with Their Cytotoxic, Molecular Modeling and Drug-Likeness Studies.

Mehmood, Rabia; Sadiq, Amina; Alsantali, Reem I; Mughal, Ehsan Ullah; Alsharif, Meshari A; Naeem, Nafeesa; Javid, Asif; Al-Rooqi, Munirah M; Chaudhry, Gul-E-Saba; Ahmed, Saleh A.

Afiliação

Mehmood R; Department of Chemistry, Govt. College Women University, Sialkot 51300, Pakistan.
Sadiq A; Department of Chemistry, Govt. College Women University, Sialkot 51300, Pakistan.
Alsantali RI; Department of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.
Mughal EU; Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan.
Alsharif MA; Department of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Naeem N; Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan.
Javid A; Department of Chemistry, University of Gujrat, Gujrat 50700, Pakistan.
Al-Rooqi MM; Department of Chemistry, Faculty of Applied Sciences, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Chaudhry GE; Institute of Marine Biotechnology, Universiti Malaysia Terengganu, Kuala Nerus 21030, Terengganu, Malaysia.
Ahmed SA; Microbiology and Biotechnology Research Lab, Fatima Jinnah Women University, Rawalpindi 23451, Pakistan.

ACS Omega ; 7(4): 3775-3795, 2022 Feb 01.

Article em En | MEDLINE | ID: mdl-35128286

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: ACS Omega Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Paquistão

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