Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury.

Meyer Zu Reckendorf, Sofia; Moser, Diana; Blechschmidt, Anna; Joga, Venkata Neeha; Sinske, Daniela; Hegler, Jutta; Deininger, Stefanie; Catanese, Alberto; Vettorazzi, Sabine; Antoniadis, Gregor; Boeckers, Tobias; Knöll, Bernd

Meyer Zu Reckendorf, Sofia; Moser, Diana; Blechschmidt, Anna; Joga, Venkata Neeha; Sinske, Daniela; Hegler, Jutta; Deininger, Stefanie; Catanese, Alberto; Vettorazzi, Sabine; Antoniadis, Gregor; Boeckers, Tobias; Knöll, Bernd.

Afiliação

Meyer Zu Reckendorf S; Institute of Neurobiochemistry, Ulm University, Ulm, 89081, Germany.
Moser D; Institute of Neurobiochemistry, Ulm University, Ulm, 89081, Germany.
Blechschmidt A; Institute of Neurobiochemistry, Ulm University, Ulm, 89081, Germany.
Joga VN; Institute of Neurobiochemistry, Ulm University, Ulm, 89081, Germany.
Sinske D; Institute of Neurobiochemistry, Ulm University, Ulm, 89081, Germany.
Hegler J; Institute of Neurobiochemistry, Ulm University, Ulm, 89081, Germany.
Deininger S; Peripheral Nerve Surgery Unit, Department of Neurosurgery, Ulm University, District Hospital, Günzburg, 89312, Germany.
Catanese A; Institute of Anatomy and Cell Biology, Ulm University, Ulm, 89081, Germany.
Vettorazzi S; Deutsches Zentrum für Neurodegenerative Erkrankungen, Ulm, 89081, Germany.
Antoniadis G; Institute of Comparative Molecular Endocrinology, Ulm University, Ulm, 89081, Germany.
Boeckers T; Peripheral Nerve Surgery Unit, Department of Neurosurgery, Ulm University, District Hospital, Günzburg, 89312, Germany.
Knöll B; Institute of Anatomy and Cell Biology, Ulm University, Ulm, 89081, Germany.

J Neurosci ; 42(12): 2474-2491, 2022 03 23.

Article em En | MEDLINE | ID: mdl-35149515

Assuntos

Traumatismos do Nervo Facial; Regeneração Nervosa; PTEN Fosfo-Hidrolase/metabolismo; Animais; Axônios/fisiologia; Traumatismos do Nervo Facial/genética; Traumatismos do Nervo Facial/patologia; Feminino; Hiperplasia/patologia; Hipertrofia/patologia; Masculino; Camundongos; Neurônios Motores/metabolismo; Regeneração Nervosa/genética; Proteína Supressora de Tumor p53

Palavras-chave

Akt; CREB; PTEN; facial nerve; motoneuron; nerve regeneration

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Traumatismos do Nervo Facial / PTEN Fosfo-Hidrolase / Regeneração Nervosa Limite: Animals Idioma: En Revista: J Neurosci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha

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