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Ghost mitochondria drive metastasis through adaptive GCN2/Akt therapeutic vulnerability.
Ghosh, Jagadish C; Perego, Michela; Agarwal, Ekta; Bertolini, Irene; Wang, Yuan; Goldman, Aaron R; Tang, Hsin-Yao; Kossenkov, Andrew V; Landis, Catherine J; Languino, Lucia R; Plow, Edward F; Morotti, Annamaria; Ottobrini, Luisa; Locatelli, Marco; Speicher, David W; Caino, M Cecilia; Cassel, Joel; Salvino, Joseph M; Robert, Marie E; Vaira, Valentina; Altieri, Dario C.
Afiliação
  • Ghosh JC; Prostate Cancer Discovery and Development Program, The Wistar Institute, Philadelphia, PA 19104.
  • Perego M; Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104.
  • Agarwal E; Prostate Cancer Discovery and Development Program, The Wistar Institute, Philadelphia, PA 19104.
  • Bertolini I; Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104.
  • Wang Y; Prostate Cancer Discovery and Development Program, The Wistar Institute, Philadelphia, PA 19104.
  • Goldman AR; Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104.
  • Tang HY; Prostate Cancer Discovery and Development Program, The Wistar Institute, Philadelphia, PA 19104.
  • Kossenkov AV; Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104.
  • Landis CJ; Prostate Cancer Discovery and Development Program, The Wistar Institute, Philadelphia, PA 19104.
  • Languino LR; Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104.
  • Plow EF; Proteomics and Metabolomics Shared Resource, The Wistar Institute, Philadelphia, PA 19104.
  • Morotti A; Proteomics and Metabolomics Shared Resource, The Wistar Institute, Philadelphia, PA 19104.
  • Ottobrini L; Bioinformatics Shared Resource, The Wistar Institute, Philadelphia, PA 19104.
  • Locatelli M; Center for Systems and Computational Biology, The Wistar Institute, Philadelphia, PA 19104.
  • Speicher DW; Prostate Cancer Discovery and Development Program, The Wistar Institute, Philadelphia, PA 19104.
  • Caino MC; Immunology, Microenvironment and Metastasis Program, The Wistar Institute, Philadelphia, PA 19104.
  • Cassel J; Prostate Cancer Discovery and Development Program, The Wistar Institute, Philadelphia, PA 19104.
  • Salvino JM; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107.
  • Robert ME; Prostate Cancer Discovery and Development Program, The Wistar Institute, Philadelphia, PA 19104.
  • Vaira V; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195.
  • Altieri DC; Division of Pathology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan 20122, Italy.
Proc Natl Acad Sci U S A ; 119(8)2022 02 22.
Article em En | MEDLINE | ID: mdl-35177476
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mitocôndrias / Metástase Neoplásica / Neoplasias Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mitocôndrias / Metástase Neoplásica / Neoplasias Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article