TSG-6 promotes Cancer Cell aggressiveness in a CD44-Dependent Manner and Reprograms Normal Fibroblasts to create a Pro-metastatic Microenvironment in Colorectal Cancer.

Liu, Binbin; Liu, Tengfei; Liu, Yiting; Feng, Xingzhi; Jiang, Xuefei; Long, Jiahui; Ye, Shubiao; Chen, Daici; Wang, Jianping; Yang, Zihuan

Liu, Binbin; Liu, Tengfei; Liu, Yiting; Feng, Xingzhi; Jiang, Xuefei; Long, Jiahui; Ye, Shubiao; Chen, Daici; Wang, Jianping; Yang, Zihuan.

Afiliação

Liu B; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, China.
Liu T; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, China.
Liu Y; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, China.
Feng X; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, China.
Jiang X; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, China.
Long J; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, China.
Ye S; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, China.
Chen D; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, China.
Wang J; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, China.
Yang Z; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, Guangdong Institute of Gastroenterology, the Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510655, China.

Int J Biol Sci ; 18(4): 1677-1694, 2022.

Article em En | MEDLINE | ID: mdl-35280699

Assuntos

Fibroblastos Associados a Câncer; Neoplasias Colorretais; Animais; Fibroblastos Associados a Câncer/metabolismo; Linhagem Celular Tumoral; Movimento Celular/genética; Neoplasias Colorretais/metabolismo; Transição Epitelial-Mesenquimal/genética; Fibroblastos/metabolismo; Regulação Neoplásica da Expressão Gênica; Transdução de Sinais/genética; Microambiente Tumoral/genética

Palavras-chave

Colorectal Cancer; Fibroblast; Metastasis; TSG-6

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Fibroblastos Associados a Câncer Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Int J Biol Sci Assunto da revista: BIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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