Mitochondrial bioenergetics in ocular fibroblasts of two myasthenia gravis cases.

Europa, Tarin A; Nel, Melissa; Lebeko, Maribanyana R; Heckmann, Jeannine M

Europa, Tarin A; Nel, Melissa; Lebeko, Maribanyana R; Heckmann, Jeannine M.

Afiliação

Europa TA; Neurology Research Group, UCT Neurosciences Institute, University of Cape Town, Cape Town, South Africa.
Nel M; Neurology Research Group, UCT Neurosciences Institute, University of Cape Town, Cape Town, South Africa.
Lebeko MR; Neurology Division, Department of Medicine, University of Cape Town, Cape Town, South Africa.
Heckmann JM; Hair and Skin Research Laboratory, Division of Dermatology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

IBRO Neurosci Rep ; 12: 297-302, 2022 Jun.

Article em En | MEDLINE | ID: mdl-35746973

Palavras-chave

AChR, acetylcholine receptor; Cq, quantitation cycle; EAMG, experimental autoimmune myasthenia gravis; ECAR, extracellular acidification rate; EOM, extraocular muscle; FCCP, carbonyl cyanide p-trifluoromethoxyphenylhydrazone; MG, myasthenia gravis; Metabolism; Mitochondria; Myasthenia gravis; NMOC, non-mitochondrial oxygen consumption; OCR, oxygen consumption rate; OP-MG, ophthalmoplegic MG; Ocular fibroblasts; Ophthalmoplegia; Oxidative stress; PL, proton leak; SD, standard deviation; SEM, standard error of the mean; SMA, smooth muscle actin; SRC, spare respiratory capacity; Sera; max resp, maximal respiration

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: IBRO Neurosci Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: África do Sul

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