Suspected opioid-induced hyperalgesia in an infant following surgery: A case report.
J Clin Pharm Ther
; 47(9): 1486-1489, 2022 Sep.
Article
em En
| MEDLINE
| ID: mdl-35968556
ABSTRACT
WHAT IS KNOWN AND OBJECTIVE:
Opioids are commonly administered to infants having surgery. Opioid induced hyperalgesia (OIH) is a known adverse effect of opioids in adults but can be difficult to identify in infants. CASESUMMARY:
A 3-month-old received high-dose fentanyl during anorectoplasty for imperforate anus. He had signs and symptoms of OIH immediately after surgery. His pain and agitation were difficult to manage but improved after he received ketamine. WHAT IS NEW ANDCONCLUSION:
OIH should be considered in infants postoperatively when pain worsens despite administration of escalating doses of opioids. Ketamine can be an effective therapeutic for OIH.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Analgésicos Opioides
/
Ketamina
Tipo de estudo:
Prognostic_studies
Limite:
Adult
/
Humans
/
Infant
/
Male
Idioma:
En
Revista:
J Clin Pharm Ther
Assunto da revista:
FARMACIA
/
TERAPEUTICA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Estados Unidos