Glycoproteomics Identifies Plexin-B3 as a Targetable Cell Surface Protein Required for the Growth and Invasion of Triple-Negative Breast Cancer Cells.

Kuhlmann, Laura; Govindarajan, Meinusha; Mejia-Guerrero, Salvador; Ignatchenko, Vladimir; Liu, Lydia Y; Grünwald, Barbara T; Cruickshank, Jennifer; Berman, Hal; Khokha, Rama; Kislinger, Thomas

Kuhlmann, Laura; Govindarajan, Meinusha; Mejia-Guerrero, Salvador; Ignatchenko, Vladimir; Liu, Lydia Y; Grünwald, Barbara T; Cruickshank, Jennifer; Berman, Hal; Khokha, Rama; Kislinger, Thomas.

Afiliação

Kuhlmann L; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario M5G 1L7, Canada.
Govindarajan M; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario M5G 1L7, Canada.
Mejia-Guerrero S; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Ignatchenko V; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario M5G 1L7, Canada.
Liu LY; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario M5G 1L7, Canada.
Grünwald BT; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario M5G 1L7, Canada.
Cruickshank J; Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada.
Berman H; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario M5G 1L7, Canada.
Khokha R; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario M5G 1L7, Canada.
Kislinger T; Princess Margaret Cancer Center, University Health Network, Toronto, Ontario M5G 1L7, Canada.

J Proteome Res ; 21(9): 2224-2236, 2022 09 02.

Article em En | MEDLINE | ID: mdl-35981243

Assuntos

Neoplasias de Mama Triplo Negativas; Moléculas de Adesão Celular; Linhagem Celular Tumoral; Proliferação de Células/genética; Humanos; Proteínas de Membrana/genética; Proteínas do Tecido Nervoso; Moléculas de Adesão de Célula Nervosa; Neoplasias de Mama Triplo Negativas/tratamento farmacológico

Palavras-chave

CRISPR-Cas9; cell surface targets; glycoproteomics; spheroids; triple-negative breast cancer; xenograft

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias de Mama Triplo Negativas Limite: Humans Idioma: En Revista: J Proteome Res Assunto da revista: BIOQUIMICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Canadá

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