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A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.
Simon, Matthew; Yang, Jiping; Gigas, Jonathan; Earley, Eric J; Hillpot, Eric; Zhang, Lei; Zagorulya, Maria; Tombline, Greg; Gilbert, Michael; Yuen, Samantha L; Pope, Alexis; Van Meter, Michael; Emmrich, Stephan; Firsanov, Denis; Athreya, Advait; Biashad, Seyed Ali; Han, Jeehae; Ryu, Seungjin; Tare, Archana; Zhu, Yizhou; Hudgins, Adam; Atzmon, Gil; Barzilai, Nir; Wolfe, Aaron; Moody, Kelsey; Garcia, Benjamin A; Thomas, David D; Robbins, Paul D; Vijg, Jan; Seluanov, Andrei; Suh, Yousin; Gorbunova, Vera.
Afiliação
  • Simon M; Department of Biology, University of Rochester, Rochester, NY, USA.
  • Yang J; Department of Obstetrics and Gynecology, Columbia University, New York, NY, USA.
  • Gigas J; Department of Biology, University of Rochester, Rochester, NY, USA.
  • Earley EJ; Biostatistics and Epidemiology, RTI International, Durham, NC, USA.
  • Hillpot E; Department of Biology, University of Rochester, Rochester, NY, USA.
  • Zhang L; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN, USA.
  • Zagorulya M; Department of Biology, University of Rochester, Rochester, NY, USA.
  • Tombline G; Department of Biology, University of Rochester, Rochester, NY, USA.
  • Gilbert M; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Yuen SL; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN, USA.
  • Pope A; Department of Obstetrics and Gynecology, Columbia University, New York, NY, USA.
  • Van Meter M; Department of Biology, University of Rochester, Rochester, NY, USA.
  • Emmrich S; Department of Biology, University of Rochester, Rochester, NY, USA.
  • Firsanov D; Department of Biology, University of Rochester, Rochester, NY, USA.
  • Athreya A; Department of Biology, University of Rochester, Rochester, NY, USA.
  • Biashad SA; Department of Biology, University of Rochester, Rochester, NY, USA.
  • Han J; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Ryu S; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Tare A; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Zhu Y; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Hudgins A; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Atzmon G; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Barzilai N; Department of Biology, Faculty of Natural Sciences, University of Haifa, Haifa, Israel.
  • Wolfe A; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Moody K; Ichor Therapeutics, Lafayette, NY, USA.
  • Garcia BA; Ichor Therapeutics, Lafayette, NY, USA.
  • Thomas DD; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Robbins PD; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN, USA.
  • Vijg J; Department of Biochemistry, Molecular Biology and Biophysics and Institute on the Biology of Aging and Metabolism, University of Minnesota, Minneapolis, MN, USA.
  • Seluanov A; Department of Genetics, Albert Einstein College of Medicine, Bronx, NY, USA.
  • Suh Y; Department of Biology, University of Rochester, Rochester, NY, USA.
  • Gorbunova V; Department of Obstetrics and Gynecology, Columbia University, New York, NY, USA.
EMBO J ; 41(21): e110393, 2022 11 02.
Article em En | MEDLINE | ID: mdl-36215696

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sirtuínas / Lamina Tipo A Tipo de estudo: Prognostic_studies Limite: Aged80 / Humans Idioma: En Revista: EMBO J Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sirtuínas / Lamina Tipo A Tipo de estudo: Prognostic_studies Limite: Aged80 / Humans Idioma: En Revista: EMBO J Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos