Double knockout CRISPR screen for cancer resistance to T cell cytotoxicity.

Park, Jonathan J; Codina, Adan; Ye, Lupeng; Lam, Stanley; Guo, Jianjian; Clark, Paul; Zhou, Xiaoyu; Peng, Lei; Chen, Sidi

Park, Jonathan J; Codina, Adan; Ye, Lupeng; Lam, Stanley; Guo, Jianjian; Clark, Paul; Zhou, Xiaoyu; Peng, Lei; Chen, Sidi.

Afiliação

Park JJ; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
Codina A; System Biology Institute, Yale University, West Haven, CI, USA.
Ye L; Center for Cancer Systems Biology, Yale University, West Haven, CI, USA.
Lam S; Combined Program in the Biological and Biomedical Sciences, Yale University, New Haven, CT, USA.
Guo J; Molecular Cell Biology, Genetics, and Development Program, Yale University, New Haven, CT, USA.
Clark P; MD-PhD Program, Yale University, New Haven, CT, USA.
Zhou X; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA.
Peng L; System Biology Institute, Yale University, West Haven, CI, USA.
Chen S; Center for Cancer Systems Biology, Yale University, West Haven, CI, USA.

J Hematol Oncol ; 15(1): 172, 2022 12 01.

Article em En | MEDLINE | ID: mdl-36456981

Assuntos

Neoplasias; Linfócitos T; Humanos; Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas; Neoplasias/genética; Imunoterapia; Mutação

Palavras-chave

CRISPR screen; Cancer immunology; Double knockout; Genetic interaction; Immunotherapy; Systems biology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Hematol Oncol Assunto da revista: HEMATOLOGIA / NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos

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