Phosphatidylethanolamines Are Associated with Nonalcoholic Fatty Liver Disease (NAFLD) in Obese Adults and Induce Liver Cell Metabolic Perturbations and Hepatic Stellate Cell Activation.

Shama, Samaa; Jang, Hyejeong; Wang, Xiaokun; Zhang, Yang; Shahin, Nancy Nabil; Motawi, Tarek Kamal; Kim, Seongho; Gawrieh, Samer; Liu, Wanqing

Shama, Samaa; Jang, Hyejeong; Wang, Xiaokun; Zhang, Yang; Shahin, Nancy Nabil; Motawi, Tarek Kamal; Kim, Seongho; Gawrieh, Samer; Liu, Wanqing.

Afiliação

Shama S; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Jang H; Cell-Based Analysis Unit, Reference Laboratory, Egyptian Drug Authority, Cairo 12618, Egypt.
Wang X; Biostatistics and Bioinformatics Core, Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA.
Zhang Y; Department of Oncology, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Shahin NN; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Motawi TK; Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Kim S; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
Gawrieh S; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.
Liu W; Biostatistics and Bioinformatics Core, Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI 48201, USA.

Int J Mol Sci ; 24(2)2023 Jan 05.

Article em En | MEDLINE | ID: mdl-36674549

Assuntos

Hepatopatia Gordurosa não Alcoólica; Humanos; Adulto; Hepatopatia Gordurosa não Alcoólica/metabolismo; Fígado/metabolismo; Fosfatidiletanolaminas/metabolismo; Células Estreladas do Fígado/metabolismo; Espectrometria de Massas em Tandem; Obesidade/metabolismo; Progressão da Doença

Palavras-chave

cell migration; fibrosis; mitochondria; non-alcoholic fatty liver disease; obesity; phosphatidylethanolamine; phospholipids

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Risk_factors_studies Limite: Adult / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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