Defective Mitochondrial Dynamics and Protein Degradation Pathways Underlie Cadmium-Induced Neurotoxicity and Cell Death in Huntington's Disease Striatal Cells.

Kamitsuka, Paul J; Ghanem, Marwan M; Ziar, Rania; McDonald, Sarah E; Thomas, Morgan G; Kwakye, Gunnar F

Kamitsuka, Paul J; Ghanem, Marwan M; Ziar, Rania; McDonald, Sarah E; Thomas, Morgan G; Kwakye, Gunnar F.

Afiliação

Kamitsuka PJ; Neuroscience Department, Oberlin College, 119 Woodland Street, Oberlin, OH 44074, USA.
Ghanem MM; Neuroscience Department, Oberlin College, 119 Woodland Street, Oberlin, OH 44074, USA.
Ziar R; Neuroscience Department, Oberlin College, 119 Woodland Street, Oberlin, OH 44074, USA.
McDonald SE; Neuroscience Department, Oberlin College, 119 Woodland Street, Oberlin, OH 44074, USA.
Thomas MG; Neuroscience Department, Oberlin College, 119 Woodland Street, Oberlin, OH 44074, USA.
Kwakye GF; Neuroscience Department, Oberlin College, 119 Woodland Street, Oberlin, OH 44074, USA.

Int J Mol Sci ; 24(8)2023 Apr 13.

Article em En | MEDLINE | ID: mdl-37108341

Assuntos

Cádmio; Doença de Huntington; Animais; Cádmio/metabolismo; Doença de Huntington/metabolismo; Proteólise; Dinâmica Mitocondrial; Corpo Estriado/metabolismo; Morte Celular; Proteína Huntingtina/genética; Proteína Huntingtina/metabolismo; Modelos Animais de Doenças

Palavras-chave

autophagy; bioenergetics; cadmium; huntington's disease; mitochondrial dynamics; neurodegeneration; neurotoxicity; ubiquitinproteasome system (UPS)

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cádmio / Doença de Huntington Limite: Animals Idioma: En Revista: Int J Mol Sci Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google