Receptor Binding-Induced Conformational Changes in Herpes Simplex Virus Glycoprotein D Permit Interaction with the gH/gL Complex to Activate Fusion.

Atanasiu, Doina; Saw, Wan Ting; Cairns, Tina M; Friedman, Harvey M; Eisenberg, Roselyn J; Cohen, Gary H

Atanasiu, Doina; Saw, Wan Ting; Cairns, Tina M; Friedman, Harvey M; Eisenberg, Roselyn J; Cohen, Gary H.

Afiliação

Atanasiu D; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Saw WT; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Cairns TM; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Friedman HM; School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Eisenberg RJ; School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Cohen GH; Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Viruses ; 15(4)2023 03 30.

Article em En | MEDLINE | ID: mdl-37112875

Assuntos

Simplexvirus; Proteínas do Envelope Viral; Simplexvirus/genética; Proteínas do Envelope Viral/metabolismo; Ligação Proteica; Glicoproteínas/metabolismo; Dissulfetos; Internalização do Vírus

Palavras-chave

HSV; antibodies; conformational changes; glycoproteins; proteinprotein interactions

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas do Envelope Viral / Simplexvirus Idioma: En Revista: Viruses Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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