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Efficacy and Imaging-Enabled Pharmacodynamic Profiling of KRAS G12C Inhibitors in Xenograft and Genetically Engineered Mouse Models of Cancer.
Lee, Catherine; Jiang, Ziyue Karen; Planken, Simon; Manzuk, Lisa K; Ortiz, Roberto; Hall, Michael; Noorbehesht, Kavon; Ram, Sripad; Affolter, Timothy; Troche, Gabriel E; Ihle, Nathan T; Johnson, Theodore; Ahn, Youngwook; Kraus, Manfred; Giddabasappa, Anand.
Afiliação
  • Lee C; Oncology Research and Development, Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Jiang ZK; Global Science & Technology - Comparative Medicine, Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Planken S; Oncology Medicinal Chemistry, Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Manzuk LK; Comparative Medicine, Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Ortiz R; BioMedicine Design, Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Hall M; BioMedicine Design, Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Noorbehesht K; Global Science & Technology - Comparative Medicine, Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Ram S; Drug Safety Research and Development Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Affolter T; Drug Safety Research and Development Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Troche GE; Oncology Research and Development, Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Ihle NT; Oncology Research and Development, Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Johnson T; Medicine Design, Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Ahn Y; Target Sciences, Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Kraus M; Oncology Research and Development, Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
  • Giddabasappa A; Global Science & Technology - Comparative Medicine, Pfizer Inc., Worldwide Research, Development and Medical, San Diego, California.
Mol Cancer Ther ; 22(7): 891-900, 2023 07 05.
Article em En | MEDLINE | ID: mdl-37186518
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cancer Ther Assunto da revista: ANTINEOPLASICOS Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Cancer Ther Assunto da revista: ANTINEOPLASICOS Ano de publicação: 2023 Tipo de documento: Article