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Integrative analysis of cancer dependency data and comprehensive phosphoproteomics data revealed the EPHA2-PARD3 axis as a cancer vulnerability in KRAS-mutant colorectal cancer.
Gunji, Daigo; Narumi, Ryohei; Muraoka, Satoshi; Isoyama, Junko; Ikemoto, Narumi; Ishida, Mimiko; Tomonaga, Takeshi; Sakai, Yoshiharu; Obama, Kazutaka; Adachi, Jun.
Afiliação
  • Gunji D; Laboratory of Proteome Research, National Institute of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan. jun_adachi@nibiohn.go.jp.
  • Narumi R; Laboratory of Proteomics for Drug Discovery, Center for Drug Design Research, National Institute of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan.
  • Muraoka S; Department of Surgery, Kyoto University Graduate School of Medicine Faculty of Medicine, Kyoto, 606-8507, Japan.
  • Isoyama J; Laboratory of Proteome Research, National Institute of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan. jun_adachi@nibiohn.go.jp.
  • Ikemoto N; Laboratory of Proteomics for Drug Discovery, Center for Drug Design Research, National Institute of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan.
  • Ishida M; Laboratory of Proteome Research, National Institute of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan. jun_adachi@nibiohn.go.jp.
  • Tomonaga T; Laboratory of Proteomics for Drug Discovery, Center for Drug Design Research, National Institute of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan.
  • Sakai Y; Laboratory of Clinical and Analytical Chemistry, Center for Drug Design Research, National Institute of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan.
  • Obama K; Laboratory of Proteome Research, National Institute of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan. jun_adachi@nibiohn.go.jp.
  • Adachi J; Laboratory of Proteomics for Drug Discovery, Center for Drug Design Research, National Institute of Biomedical Innovation, Health and Nutrition, Osaka, 567-0085, Japan.
Mol Omics ; 19(8): 624-639, 2023 09 25.
Article em En | MEDLINE | ID: mdl-37232035
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteínas Proto-Oncogênicas p21(ras) Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Omics Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Proteínas Proto-Oncogênicas p21(ras) Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Omics Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão