Optical, structural and antibacterial properties of silver nanoparticles and DNA-templated silver nanoclusters.
Nanomedicine (Lond)
; 18(9): 769-782, 2023 04.
Article
em En
| MEDLINE
| ID: mdl-37345552
ABSTRACT
Silver nanoparticles (AgNPs) are increasingly considered for biomedical applications as drug-delivery carriers, imaging probes and antibacterial agents. Silver nanoclusters (AgNCs) represent another subclass of nanoscale silver. AgNCs are a promising tool for nanomedicine due to their small size, structural homogeneity, antibacterial activity and fluorescence, which arises from their molecule-like electron configurations. The template-assisted synthesis of AgNCs relies on organic molecules that act as polydentate ligands. In particular, single-stranded nucleic acids reproducibly scaffold AgNCs to provide fluorescent, biocompatible materials that are incorporable in other formulations. This mini review outlines the design and characterization of AgNPs and DNA-templated AgNCs, discusses factors that affect their physicochemical and biological properties, and highlights applications of these materials as antibacterial agents and biosensors.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ácidos Nucleicos
/
Técnicas Biossensoriais
/
Nanopartículas Metálicas
Idioma:
En
Revista:
Nanomedicine (Lond)
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Estados Unidos