The mechanism of action and biodistribution of a novel EGFR/VEGF bispecific fusion protein that exhibited superior antitumor activities.

Deng, Lan; Wang, Lihua; Zhang, Jinzhao; Zhao, Le; Meng, Yun; Zheng, Jidai; Xu, Wei; Zhu, Zhenping; Huang, Haomin

Deng, Lan; Wang, Lihua; Zhang, Jinzhao; Zhao, Le; Meng, Yun; Zheng, Jidai; Xu, Wei; Zhu, Zhenping; Huang, Haomin.

Afiliação

Deng L; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd. a 3SBio Inc. Company, 399 Libing Road, Shanghai, 201203, China.
Wang L; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd. a 3SBio Inc. Company, 399 Libing Road, Shanghai, 201203, China.
Zhang J; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd. a 3SBio Inc. Company, 399 Libing Road, Shanghai, 201203, China.
Zhao L; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd. a 3SBio Inc. Company, 399 Libing Road, Shanghai, 201203, China.
Meng Y; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd. a 3SBio Inc. Company, 399 Libing Road, Shanghai, 201203, China.
Zheng J; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd. a 3SBio Inc. Company, 399 Libing Road, Shanghai, 201203, China.
Xu W; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd. a 3SBio Inc. Company, 399 Libing Road, Shanghai, 201203, China.
Zhu Z; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd. a 3SBio Inc. Company, 399 Libing Road, Shanghai, 201203, China.
Huang H; Sunshine Guojian Pharmaceutical (Shanghai) Co. Ltd. a 3SBio Inc. Company, 399 Libing Road, Shanghai, 201203, China.

Heliyon ; 9(6): e16922, 2023 Jun.

Article em En | MEDLINE | ID: mdl-37484224

Palavras-chave

Anticancer therapy; Biodistribution; EGFR; Endocytosis; VEGF; VEGFR inhibitor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Heliyon Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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