Affibody-based hBCMA x CD16 dual engagers for NK cell-mediated killing of multiple myeloma cells.

Giang, Kim Anh; Boxaspen, Thorstein; Diao, Yumei; Nilvebrant, Johan; Kosugi-Kanaya, Mizuha; Kanaya, Minoru; Krokeide, Silje Zandstra; Lehmann, Fredrik; Svensson Gelius, Stefan; Malmberg, Karl-Johan; Nygren, Per-Åke

Giang, Kim Anh; Boxaspen, Thorstein; Diao, Yumei; Nilvebrant, Johan; Kosugi-Kanaya, Mizuha; Kanaya, Minoru; Krokeide, Silje Zandstra; Lehmann, Fredrik; Svensson Gelius, Stefan; Malmberg, Karl-Johan; Nygren, Per-Åke.

Afiliação

Giang KA; Department of Protein Science, Div. Protein Engineering, AlbaNova University Center, KTH Royal Institute of Technology, S-114 21 Stockholm, Sweden.
Boxaspen T; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, N-0424 Oslo, Norway; Precision Immunotherapy Alliance, Institute of Clinical Medicine, University of Oslo, N-0313 Oslo, Norway.
Diao Y; Oncopeptides AB, S-171 48 Stockholm, Sweden.
Nilvebrant J; Department of Protein Science, Div. Protein Engineering, AlbaNova University Center, KTH Royal Institute of Technology, S-114 21 Stockholm, Sweden.
Kosugi-Kanaya M; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, N-0424 Oslo, Norway; Precision Immunotherapy Alliance, Institute of Clinical Medicine, University of Oslo, N-0313 Oslo, Norway.
Kanaya M; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, N-0424 Oslo, Norway; Precision Immunotherapy Alliance, Institute of Clinical Medicine, University of Oslo, N-0313 Oslo, Norway.
Krokeide SZ; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, N-0424 Oslo, Norway; Precision Immunotherapy Alliance, Institute of Clinical Medicine, University of Oslo, N-0313 Oslo, Norway.
Lehmann F; Oncopeptides AB, S-171 48 Stockholm, Sweden.
Svensson Gelius S; Oncopeptides AB, S-171 48 Stockholm, Sweden.
Malmberg KJ; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, N-0424 Oslo, Norway; Precision Immunotherapy Alliance, Institute of Clinical Medicine, University of Oslo, N-0313 Oslo, Norway. Electronic address: k.j.malmberg@medisin.uio.no.
Nygren PÅ; Department of Protein Science, Div. Protein Engineering, AlbaNova University Center, KTH Royal Institute of Technology, S-114 21 Stockholm, Sweden; Science For Life Laboratory, S-171 65 Solna, Sweden. Electronic address: perake@kth.se.

N Biotechnol ; 77: 139-148, 2023 Nov 25.

Article em En | MEDLINE | ID: mdl-37673373

Palavras-chave

Affibody; BCMA; CD16; Dual engager; Multiple myeloma; NK cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: N Biotechnol Assunto da revista: BIOLOGIA MOLECULAR / ENGENHARIA BIOMEDICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Suécia

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