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PAM-flexible genome editing with an engineered chimeric Cas9.
Zhao, Lin; Koseki, Sabrina R T; Silverstein, Rachel A; Amrani, Nadia; Peng, Christina; Kramme, Christian; Savic, Natasha; Pacesa, Martin; Rodríguez, Tomás C; Stan, Teodora; Tysinger, Emma; Hong, Lauren; Yudistyra, Vivian; Ponnapati, Manvitha R; Jacobson, Joseph M; Church, George M; Jakimo, Noah; Truant, Ray; Jinek, Martin; Kleinstiver, Benjamin P; Sontheimer, Erik J; Chatterjee, Pranam.
Afiliação
  • Zhao L; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
  • Koseki SRT; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
  • Silverstein RA; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Amrani N; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.
  • Peng C; Biological and Biomedical Sciences Program, Harvard University, Boston, MA, USA.
  • Kramme C; RNA Therapeutics Institute, University of Massachusetts Medical School, Cambridge, USA.
  • Savic N; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Canada.
  • Pacesa M; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA, USA.
  • Rodríguez TC; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Canada.
  • Stan T; Department of Biochemistry, University of Zurich, Zürich, Switzerland.
  • Tysinger E; RNA Therapeutics Institute, University of Massachusetts Medical School, Cambridge, USA.
  • Hong L; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
  • Yudistyra V; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
  • Ponnapati MR; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
  • Jacobson JM; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
  • Church GM; Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Jakimo N; Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Truant R; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA, USA.
  • Jinek M; Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Kleinstiver BP; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Canada.
  • Sontheimer EJ; Department of Biochemistry, University of Zurich, Zürich, Switzerland.
  • Chatterjee P; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Nat Commun ; 14(1): 6175, 2023 10 04.
Article em En | MEDLINE | ID: mdl-37794046
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas CRISPR-Cas / Edição de Genes Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas CRISPR-Cas / Edição de Genes Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos